About   Help   FAQ
En1tm1.1(flpo)Jbb - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
En1tm1.1(flpo)Jbb
engrailed 1; targeted mutation 1.1, Jay B Bikoff 		Driver: En1
Type: Targeted (Null/knockout, Recombinase)
Synonym: En1-Flpo, En1::Flpo
Molecular description: Flpo, a codon-optimized version of Flp recombinase was inserted into the ATG in the 1st exon of the En1 genomic locus. Positive ES cell clones were screened by Southern blot analysis and microinjected into blastocysts, and the resulting chimeric mice were crossed to C57BL/6J females. The neomycin selectable cassette was removed using Protamine::Cre mice.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:313825 Fig. 4
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory