Pdgfrb<tm1.2(flpo)Leol> - Integumental System Recombinase Activity Detail MGI Mouse

Pdgfrb^{tm1.2(flpo)Leol} - Integumental System
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Pdgfrb^{tm1.2(flpo)Leol}
platelet derived growth factor receptor, beta polypeptide; targeted mutation 1.2, Lorin E Olson

Driver: Pdgfrb
Type: Targeted (Null/knockout, Recombinase)

Synonym:

bR^deltaFlp, Pdgfrb^detalFlp

Molecular description:

The targeting cassette consisting of a SA.lox.PDGFRb.lox-Flpo-attB-Neo-attP cassette replaced the exons 2-4 of the endogenous Pdgfrb gene. The PDGFRb is a mouse Pdgfrb gene cDNA. PhiC31 integrase removed the attB-Neo-attP cassette. Cre-mediated recombination removed lox.PDGFRb.lox cassette from Pdgfrb^{tm1.1(flpo)Leol} to enable the expression of the flpo recombinase. This is a nock-in-nock-out null allele.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Pdgfrb^{tm1.2(flpo)Leol} activity also observed in:
adipose tissue

Tissue Information

Integumental System

Other recombinase alleles with activity in Integumental System tissues:

Agrp^tm1(cre)Lowl, Aire^tm3(cre)Mmat, Alpl^tm1(cre)Nagy, Atoh8^{tm1(EGFP/cre)Gasa} ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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