Pomc<tm1.1(cre)Lowl> - Nervous System Recombinase Activity Detail MGI Mouse

Pomc^{tm1.1(cre)Lowl} - Nervous System
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Pomc^{tm1.1(cre)Lowl}
pro-opiomelanocortin-alpha; targeted mutation 1.1, Bradford B Lowell

Driver: Pomc
Type: Targeted (No functional change, Recombinase)

Synonym:

Pomc-IRES-Cre

Molecular description:

A selection cassette containing an internal ribosomal entry sequence (IRES) linked to Cre-recombinase and an Frt-flanked kanamycin resistance gene was targeted just downstream of the stop codon of the Pomc gene, so that Cre-recombinase expression was driven by the endogenous gene. Flpe recombinase transgene mice were then used to remove the kanamycin selection cassette.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Pomc^{tm1.1(cre)Lowl} activity also observed in:
head

Tissue Information

Nervous System

Other recombinase alleles with activity in Nervous System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acsm4^tm1(cre)Hsak, Adcyap1r1^{tm1.1(cre/GFP)Rpa} ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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