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Tnctm1(cre/ERT2)Cmha - Renal & Urinary System
Recombinase Activity Detail
Allele Information
Allele:
Tnctm1(cre/ERT2)Cmha
tenascin C; targeted mutation 1, Chuan-Ming Hao 		Driver: Tnc
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Tenascin-C-CreER2, TncYFP-CreER
Molecular description: Using homologous recombination, a cre/ERT2-IRES-EGFP cassette was inserted immediately upstream of the translation start ATG codon in exon 2 of the tenascin C gene. A neo selection marker flanked by frt sites followed the cre cassette. EGFP expression is similar to endogenous Tnc expression in the kidney inner medulla interstitial cells. No significant cre-dependent reporter activity is observed in absence of tamoxifen treatment.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tnctm1(cre/ERT2)Cmha activity also observed in:
head, nervous system
Tissue Information
Renal & Urinary System Other recombinase alleles with activity in Renal & Urinary System tissues:
Images
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J:202522 Fig. 4 J:202522 Fig. 4b J:202522 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory