Tg(TNS4-cre)1Shlo - Cardiovascular System Recombinase Activity Detail MGI Mouse

Tg(TNS4-cre)1Shlo - Cardiovascular System
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Tg(TNS4-cre)1Shlo
transgene insertion 1, Su Hao Lo

Driver: TNS4
Type: Transgenic (Recombinase)

Synonym:

pCTEN-Cre

Molecular description:

The final transgenic construct contained a 327-bp fragment from -290 to +37, of the human TNS4 (tensin 4; CTEN) promoter, a synthetic intron sequence, cre recombinase cDNA with a nuclear localization signal, and an SV40 polyadenylation signal. The construct was microinjected into (C57BL/6 x CBA)F1 zygotes. No founder information or line numbers are available. Crosses with reporter mice show strong cre activity in the brain and prostate, occasional staining in islets in the pancreas, bronchiole epithelium of the lung and in some tubules of the testis. No activity is observed in the kidney, small intestine, thymus, heart, tongue, liver, spleen or mammary gland.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Tg(TNS4-cre)1Shlo activity also observed in:
alimentary system, head, nervous system, renal & urinary system, reproductive system, respiratory system

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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