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Tg(Pitx2-cre/ERT2)#Jfm - Respiratory System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pitx2-cre/ERT2)#Jfm
transgene insertion, James F Martin
Driver: Pitx2
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Pitx2cCreERT2
Molecular description: The construct contains a 16 kilo-base-long Pitx2 mouse 129SV genomic fragment encompassing the Pitx2 promoter and 4.2 kb downstream of exon 6. A promotor-less CreERT2 cassette, including the CreERT2 coding sequence and a poly(A) tail, was cloned into the 5' region of Pitx2 exon 4. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pitx2-cre/ERT2)#Jfm activity also observed in:
cardiovascular system
Tissue Information
Respiratory System Other recombinase alleles with activity in Respiratory System tissues:
Images
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J:310646 Fig. 1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory