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pH2.3 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pH2.3
  • Sequence Type
    genomic
  • ID
    MGI:11599
  • Region Covered
    includes the entire coding region
  • Vector Type
    Plasmid
  • Insert Site
    BamHI/HindIII
  • Insert Size
    2.3kb
  • Other IDs
    57494 (ATCC)
Source
  • Species
    human
Genes
Hspa2 heat shock protein 2
Hspa1b heat shock protein 1B
Sequences
Polymorphisms
J:10825 Gaskins HR, et al., Immunogenetics. 1990;32(4):286-9
Notes: Using DraI, alleles a and d were indistinguishable and alleles b and c were indistinguishable. KpnI will distinguish between the NON/Lt and NOD/Lt strains.
Endonuclease Gene Allele Fragments Strains
DraI Hspa1b a 8.5kb A/J, BALB/cByJ, C3H/HeJ, C57BL/6J, DBA/2J, NON/ShiLt, NZB/BlNJ, NZW/LacJ, PL/J, RIIIS/J, SJL/J
b 7.0kb SM/J, SWR/J
c 7.0kb NOD/ShiLt
d 8.5kb M. spretus
EcoRI Hspa1b a 7.5kb C57L/J, SJL/J
b 6kb SWR/J
SacI Hspa1b a 12,16kb A/J, BALB/cByJ, C3H/HeJ, C57BL/6J, DBA/2J, NON/ShiLt, NZB/BlNJ, NZW/LacJ, PL/J, RIIIS/J, SJL/J
b 16,17kb SM/J, SWR/J
c 16kb NOD/ShiLt
d 8.4,19kb M. spretus
J:18817 Khan F, et al., Genomics. 1994 May 1;21(1):128-37
Endonuclease Gene Allele Fragments Strains
EcoRI Hspa2 a 6.6kb AKR/J, DBA/2J, SM/J
b 5.5kb BALB/cJ, C3H/HeJ, C57BL/6J, C57L/J, NZB/BlNJ, O20/A, SJL/J, SWR/J
References
J:15357 Hunt C, et al., Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70. Proc Natl Acad Sci U S A. 1985 Oct;82(19):6455-9
J:15358 Krawczyk Z, et al., A hsp70-related gene is constitutively highly expressed in testis of rat and mouse. Mol Biol Rep. 1987;12(1):27-34
J:10825 Gaskins HR, et al., Localization of a mouse heat shock Hsp70 gene within the H-2 complex. Immunogenetics. 1990;32(4):286-9
J:1314 Lafuse WP, et al., PFGE mapping and RFLP analysis of the S/D region of the mouse H-2 complex. Immunogenetics. 1992;36(2):110-6
J:18817 Khan F, et al., Refinement of the DNA marker maps of mouse chromosome 12. Genomics. 1994 May 1;21(1):128-37

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory