Mef2d Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mef2d
myocyte enhancer factor 2D
MGI:99533

16 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Crx^tm1Clc/Crx^tm1Clc Mef2d^tm1.2Tfur/Mef2d^tm1.2Tfur involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal retina bipolar cell morphology	J:230346
	abnormal retina outer plexiform layer morphology	J:230346
	abnormal retina photoreceptor morphology	J:230346
	absent photoreceptor inner segment	J:230346
Mef2a^tm1.1Limm/Mef2a^tm1.1Limm Mef2c^tm2Eno/Mef2c^tm2Eno Mef2d^tm3Eno/Mef2d^tm3Eno Tg(GFAP-cre)25Mes/0 involves: 129S/SvEv * C57BL/6 * FVB/N	abnormal long-term potentiation	J:207812
	decreased body weight	J:207812
	decreased brain size	J:207812
	enhanced paired-pulse facilitation	J:207812
	increased neuron apoptosis	J:207812
	normal nervous system phenotype	J:207812
	premature death	J:207812
Mef2a^tm1.1Limm/Mef2a^tm1.1Limm Mef2d^tm3Eno/Mef2d^tm3Eno Tg(GFAP-cre)25Mes/0 involves: 129S/SvEv * C57BL/6 * FVB/N	normal behavior/neurological phenotype	J:207812
	enhanced paired-pulse facilitation	J:207812
	impaired coordination	J:207812
	normal nervous system phenotype	J:207812
Mef2c^tm1Eno/Mef2c⁺ Mef2d^tm1.1Eno/Mef2d⁺ involves: 129S7/SvEvBrd	failure of sternum ossification	J:119152
	neonatal lethality, complete penetrance	J:119152
Mef2c^tm2Eno/Mef2c^tm2Eno Mef2d^tm1Eno/Mef2d^tm1Eno Tg(Col2a1-cre)1Bhr/0 involves: 129S/SvEv * C57BL/6 * SJL	failure of endochondral bone ossification	J:119152

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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