Wnt7a Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Wnt7a
wingless-type MMTV integration site family, member 7A
MGI:98961

20 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ Wnt7a^tm1Amc/Wnt7a^tm1Amc Wnt7b^tm1Parr/Wnt7b^tm2Amc involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	abnormal blood-brain barrier function	J:142352
	abnormal vasculogenesis	J:142352
	embryonic lethality during organogenesis, complete penetrance	J:142352
	intracranial hemorrhage	J:142352
	spinal hemorrhage	J:142352
En1^tm1Alj/En1^tm1Alj Wnt7a^tm1Amc/Wnt7a^tm1Amc Tg(Wnt1-En1)1Amc/0 either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)	abnormal autopod morphology	J:45301
	abnormal digit morphology	J:45301
	abnormal foot pad morphology	J:45301
	abnormal forelimb morphology	J:45301
	oligodactyly	J:45301
	perinatal lethality, incomplete penetrance	J:45301
	premature death	J:45301
Tg(Nes-cre)1Kln/0 Wnt7a^tm1Amc/Wnt7a^tm1Amc Wnt7b^tm1Parr/Wnt7b^tm2Amc involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal blood-brain barrier function	J:142352
	abnormal vasculogenesis	J:142352
	embryonic lethality during organogenesis, complete penetrance	J:142352
	intracranial hemorrhage	J:142352
	spinal hemorrhage	J:142352
Wnt7a^px-J/Wnt7a^px-J C57BL/6J-Wnt7a^px-J/GrsrJ	abnormal forelimb morphology	J:188477
	abnormal limb development	J:188477
	abnormal sperm motility	J:188477
	female infertility	J:188477
	normal hearing/vestibular/ear phenotype	J:188477
	hemimelia	J:188477
	male infertility	J:188477
	oligodactyly	J:188477
	short forelimb	J:188477
	normal vision/eye phenotype	J:188477

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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