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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tnni3
troponin I, cardiac 3
MGI:98783
42 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Myh6tm1Jse/Myh6+
Tg(Myh6-TNNI3*G203S)1Chs/0
involves: 129X1/SvJ * C57BL/6
abnormal atrial thrombosis J:153302
abnormal cardiac muscle tissue morphology J:153302
abnormal heart echocardiography feature J:153302
abnormal myocardial fiber morphology J:153302
abnormal P wave J:153302
atrioventricular block J:153302
cardiac interstitial fibrosis J:153302
cardiac muscle necrosis J:153302
congestive heart failure J:153302
decreased cardiac muscle contractility J:153302
dilated cardiomyopathy J:153302
dilated heart J:153302
dilated heart atrium J:153302
enlarged myocardial fiber J:153302
increased heart weight J:153302
increased lung weight J:153302
irregular heartbeat J:153302
liver inflammation J:153302
liver vascular congestion J:153302
lung inflammation J:153302
myocardial fiber degeneration J:153302
postnatal lethality, complete penetrance J:153302
prolonged PR interval J:153302
prolonged QT interval J:153302
prolonged RR interval J:153302
pulmonary vascular congestion J:153302
Tg(Myh6-Tnni3*)1Ammu/0
involves: A/J * C57BL/6
abnormal cardiac muscle relaxation J:59433
abnormal enzyme/coenzyme activity J:104770
abnormal heart echocardiography feature J:59433, J:104770
abnormal myocardial fiber physiology J:59433, J:104770
abnormal myocardium layer morphology J:59433
decreased cardiac muscle contractility J:59433, J:104770
decreased heart rate J:59433
decreased physiological sensitivity to xenobiotic J:59433
dilated cardiomyopathy J:104770
dilated heart left ventricle J:59433, J:104770
dilated heart ventricle J:59433
enlarged heart J:59433
increased heart weight J:59433
increased sensitivity to xenobiotic induced morbidity/mortality J:59433
normal mortality/aging J:59433
Tg(Myh6-TNNI3*G203S)1Chs/0
Not Specified
abnormal impulse conducting system conduction J:114537
abnormal myocardial fiber morphology J:114537
abnormal myocardial fiber physiology J:114537
abnormal QRS complex J:114537
cardiac hypertrophy J:114537
cardiac interstitial fibrosis J:114537
cardiomyopathy J:114537
heart left ventricle hypertrophy J:114537
prolonged PR interval J:114537
Tg(Myh6-TNNI3*G203S)4Chs/0
Not Specified
abnormal impulse conducting system conduction J:114537
abnormal myocardial fiber morphology J:114537
abnormal myocardial fiber physiology J:114537
abnormal QRS complex J:114537
cardiac hypertrophy J:114537
cardiac interstitial fibrosis J:114537
cardiomyopathy J:114537
heart left ventricle hypertrophy J:114537
prolonged PR interval J:114537

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory