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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sim1
single-minded family bHLH transcription factor 1
MGI:98306
6 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm2(GFP/tetX)Gld/Gt(ROSA)26Sor+
Sim1tm1.1(cre)Gld/Sim1+
involves: C57BL/6 * SJL 		abnormal CNS synaptic transmission J:147245
Sim1tm1.1(cre)Gld/Sim1+
Tg(CAG-Bgeo,-AlstR,-EGFP)192Gld/0
involves: 129S1/Sv * C57BL/6 * SJL 		abnormal CNS synaptic transmission J:147245
abnormal gait J:147245
Sim1tm1Fan/Sim1+
Sim2tm1Fan/Sim2+
involves: 129/Sv * C57BL/6 		abnormal diencephalon morphology J:76787
increased susceptibility to weight gain J:76787
Sim1tm1Fan/Sim1+
Sim2tm1Fan/Sim2tm1Fan
involves: 129S1/Sv * 129X1/SvJ 		abnormal nervous system tract morphology J:104419
Sim1tm1Fan/Sim1tm1Fan
Sim2tm1Fan/Sim2+
involves: 129S1/Sv * 129X1/SvJ 		abnormal nervous system tract morphology J:104419
Sim1tm1Fan/Sim1tm1Fan
Sim2tm1Fan/Sim2tm1Fan
involves: 129S1/Sv * 129X1/SvJ 		abnormal nervous system tract morphology J:104419
Sim1tm1Fan/Sim1tm1Jlmd
Sim2tm1Fan/Sim2tm1Fan
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal axon morphology J:104419
Sim1tm1Jlmd/Sim1tm1Jlmd
Sim2tm1Fan/Sim2tm1Fan
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal nervous system tract morphology J:104419
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory