Scp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Scp2
sterol carrier protein 2, liver
MGI:98254

24 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Scp2^tm1Fsch/Scp2^tm1Fsch B6.129P2-Scp2^tm1Fsch	abnormal hepatocyte morphology	J:126573
Scp2^tm1Kier/Scp2^tm1Kier involves: 129P2/OlaHsd * C57BL/6NCr	abnormal lipid level	J:124895
	abnormal liver morphology	J:124895
	decreased circulating triglyceride level	J:124895
	decreased hepatocyte number	J:124895
	decreased lean body mass	J:124895
	decreased liver triglyceride level	J:124895
	decreased total body fat amount	J:124895
	enlarged liver	J:124895
	increased circulating cholesterol level	J:124895
	increased fatty acids level	J:124895
	increased susceptibility to weight loss	J:124895
	liver inflammation	J:124895
Scp2^tm1Usee/Scp2^tm1Usee involves: 129P2/OlaHsd * C57BL/6	abnormal bile salt level	J:73460
	abnormal bile secretion	J:73460
	abnormal circulating cholesterol level	J:73460
	abnormal food intake	J:47280
	abnormal lipid level	J:47280
	decreased circulating free fatty acids level	J:47280
	decreased liver cholesterol level	J:47280, J:73460
	decreased liver triglyceride level	J:47280
	normal growth/size/body region phenotype	J:47280
	increased circulating HDL cholesterol level	J:73460
	increased circulating LDL cholesterol level	J:73460
	increased circulating triglyceride level	J:47280
	increased circulating VLDL cholesterol level	J:73460
	increased fatty acids level	J:47280

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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