Oprl1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Oprl1
opioid receptor-like 1
MGI:97440

24 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Oprl1^em1(IMPC)Mbp/Oprl1^em1(IMPC)Mbp C57BL/6N-Oprl1^em1(IMPC)Mbp/MbpMmucd	abnormal eye morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	enlarged spleen	J:211773
	increased mean platelet volume	J:211773
	increased red blood cell distribution width	J:211773
	microphthalmia	J:211773
	small liver	J:211773
Oprl1^tm1Dgen/Oprl1^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:101679
Oprl1^tm1Hta/Oprl1^tm1Hta involves: 129S4/SvJae	abnormal mechanical nociception	J:107151
Oprl1^tm1Hta/Oprl1^tm1Hta involves: 129S4/SvJae * C57BL/6J	abnormal chemical nociception	J:39955, J:89677
	abnormal learning/memory/conditioning	J:49161
	abnormal passive avoidance behavior	J:49161
	abnormal response to new environment	J:49161
	abnormal spatial learning	J:49161
	abnormal touch/ nociception	J:39955
	decreased chemically-elicited antinociception	J:70569
	decreased thermal nociceptive threshold	J:89677
	enhanced long-term potentiation	J:49161
	impaired behavioral response to morphine	J:70568
	increased dopamine level	J:90602
	increased susceptibility to noise-induced hearing loss	J:39955

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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