Slc10a1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc10a1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
MGI:97379

23 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc10a1^em1(IMPC)Mbp/Slc10a1^em1(IMPC)Mbp C57BL/6N-Slc10a1^em1(IMPC)Mbp/MbpMmucd	abnormal gallbladder morphology	J:211773
	abnormal heart morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal seminal vesicle morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	enlarged gallbladder	J:211773
	enlarged heart	J:211773
	small seminal vesicle	J:211773
Slc10a1^tm1Tac/Slc10a1^tm1Tac either: B6.Cg-Slc10a1^tm1Tac or (involves: 129S/SvEv * C57BL/6J)	abnormal bile salt homeostasis	J:274149
	abnormal bile secretion	J:274149
	abnormal feces composition	J:274149
	abnormal urine homeostasis	J:274149
	abnormal xenobiotic pharmacokinetics	J:274149
	decreased body weight	J:274149
	decreased physiological sensitivity to xenobiotic	J:274149
	normal homeostasis/metabolism phenotype	J:274149
	increased bile salt level	J:274149
	increased circulating alkaline phosphatase level	J:274149
	increased circulating bilirubin level	J:274149
	increased susceptibility to induced morbidity/mortality	J:274149
	normal liver/biliary system phenotype	J:274149

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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