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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Nfe2
nuclear factor, erythroid derived 2
MGI:97308
24 phenotypes from 1 allele in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Nfe2tm1Sho/Nfe2+
C.129S4-Nfe2tm1Sho
enlarged spleen J:125982
increased incidence of induced tumors J:125982
increased sensitivity to induced morbidity/mortality J:125982
increased susceptibility to viral infection J:125982
Nfe2tm1Sho/Nfe2tm1Sho
involves: 129/Sv * 129S4/SvJae
abnormal hematopoietic system physiology J:20132, J:106670
abnormal megakaryocyte morphology J:20132, J:106670
absent platelets J:20132
anemia J:20132
decreased body size J:20132
decreased hemoglobin content J:20132
decreased survivor rate J:20132
increased bone ossification J:111270
increased compact bone mass J:111270
increased megakaryocyte cell number J:20132
increased osteoblast cell number J:111270
increased osteoclast cell number J:111270
increased trabecular bone volume J:111270
internal hemorrhage J:20132
microcytosis J:20132
neonatal lethality, incomplete penetrance J:20132
pallor J:20132
postnatal lethality, incomplete penetrance J:20132
thrombocytopenia J:106670
Nfe2tm1Sho/Nfe2tm1Sho
involves: 129S4/SvJae * C57BL/6J
abnormal hematopoietic system physiology J:20132
abnormal megakaryocyte morphology J:20132
absent platelets J:20132
anemia J:20132
decreased body size J:20132
decreased hemoglobin content J:20132
decreased survivor rate J:20132
enhanced megakaryocyte emperipolesis J:20132
increased megakaryocyte cell number J:20132
internal hemorrhage J:20132
microcytosis J:20132
neonatal lethality, incomplete penetrance J:20132
pallor J:20132

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory