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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lipa
lysosomal acid lipase A
MGI:96789
74 phenotypes from 2 alleles in 2 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Lipatm1c(EUCOMM)Hmgu/Lipatm1c(EUCOMM)Hmgu
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1Tg(Alb-cre)21Mgn
involves: C57BL/6J * C57BL/6N * C57BL/6NTac
abnormal carbohydrate metabolism J:270182
abnormal enzyme/coenzyme activity J:270182
abnormal hepatocyte morphology J:270182
abnormal lipid oxidation J:270182
abnormal tricarboxylic acid cycle J:270182
normal adipose tissue phenotype J:270182
decreased gonadal fat pad weight J:270182
decreased liver triglyceride level J:270182
decreased susceptibility to diet-induced obesity J:270182
decreased triglyceride lipase activity J:270182
decreased unsaturated fatty acids level J:270182
enlarged liver J:270182
hepatic steatosis J:270182
impaired gluconeogenesis J:270182
improved glucose tolerance J:270182
increased circulating alanine transaminase level J:270182
increased circulating aspartate transaminase level J:270182
increased circulating cholesterol level J:270182
increased circulating ketone body level J:270182
increased circulating LDL cholesterol level J:270182
increased insulin sensitivity J:270182
increased liver cholesterol level J:270182
increased liver weight J:270182
increased respiratory quotient J:270182
increased unsaturated fatty acids level J:270182
liver fibrosis J:270182
liver inflammation J:270182
pale liver J:270182
Lipatm1Ggb/Lipatm1Ggb
involves: 129P2/OlaHsd * CF-1
abnormal adrenal gland morphology J:49674
abnormal alveolar macrophage morphology J:101217
abnormal brown adipose tissue morphology J:68812
abnormal choroid plexus morphology J:68812
abnormal duodenum morphology J:68812
abnormal hepatocyte morphology J:49674, J:68812
abnormal inguinal fat pad morphology J:68812
abnormal interscapular fat pad morphology J:68812
abnormal intestinal mucosa morphology J:49674
abnormal intestine morphology J:49674
abnormal jejunum morphology J:68812
abnormal Kupffer cell morphology J:68812
abnormal lipid level J:68812
abnormal liver morphology J:49674
abnormal liver sinusoid morphology J:49674
abnormal lung morphology J:68812
abnormal pulmonary alveolus morphology J:101217
abnormal retroperitoneal fat pad morphology J:68812
abnormal small intestinal villus morphology J:68812
abnormal small intestine morphology J:68812
abnormal spleen morphology J:49674, J:68812
abnormal type II pneumocyte morphology J:101217
abnormal white fat cell size J:68812
absent subcutaneous adipose tissue J:68812
chronic inflammation J:101217
decreased body weight J:49674
decreased brown adipose tissue amount J:68812
decreased circulating HDL cholesterol level J:68812
decreased epididymal fat pad weight J:68812
decreased subcutaneous adipose tissue amount J:68812
decreased white adipose tissue amount J:68812
emphysema J:101217
enlarged mesenteric lymph nodes J:68812
enlarged spleen J:68812
hepatic steatosis J:68812
hepatosplenomegaly J:68812
increased brown fat cell lipid droplet size J:68812
increased circulating free fatty acids level J:68812
increased circulating insulin level J:68812
increased circulating LDL cholesterol level J:68812
increased club cell number J:101217
increased food intake J:68812
increased liver cholesterol level J:49674
increased liver triglyceride level J:49674
increased liver weight J:49674, J:68812
increased spleen weight J:49674, J:68812
increased type II pneumocyte number J:101217
insulin resistance J:68812
lung inflammation J:101217
pale kidney J:68812
premature death J:68812

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory