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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lcat
lecithin cholesterol acyltransferase
MGI:96755
28 phenotypes from 3 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Lcattm1Hgc/Lcat+
involves: C57BL/6 * DBA
abnormal circulating protein level J:41208
decreased circulating cholesterol level J:41208
Lcattm1Hgc/Lcattm1Hgc
involves: 129 * C57BL/6 * C57BL/6J * SJL
abnormal renal glomerulus morphology J:93775
expanded mesangial matrix J:93775
mesangial cell hyperplasia J:93775
Lcattm1Hgc/Lcattm1Hgc
involves: 129P2/OlaHsd * C57BL/6 * DBA
abnormal cholesterol homeostasis J:75567
abnormal circulating protein level J:75567
abnormal lipid homeostasis J:75567
decreased circulating HDL cholesterol level J:75567
Lcattm1Hgc/Lcattm1Hgc
involves: C57BL/6 * DBA
abnormal adrenal gland morphology J:41208
abnormal circulating protein level J:41208
abnormal lipid homeostasis J:41208
abnormal lipid level J:41208
decreased cholesterol level J:41208
decreased circulating cholesterol level J:41208
decreased circulating HDL cholesterol level J:41208
increased cholesterol level J:41208
Lcattm1Nsa/Lcat+
B6.Cg-Lcattm1Nsa
normal renal/urinary system phenotype J:69299
Lcattm1Nsa/Lcat+
involves: 129X1/SvJ * C57BL/6J
abnormal cholesterol homeostasis J:39237
abnormal lipid level J:39237
decreased circulating cholesterol level J:39237
decreased circulating HDL cholesterol level J:39237
increased circulating triglyceride level J:39237
Lcattm1Nsa/Lcattm1Nsa
B6.Cg-Lcattm1Nsa
abnormal circulating phospholipid level J:69299
abnormal erythrocyte osmotic lysis J:69299
abnormal kidney afferent arteriole morphology J:69299
abnormal lipid level J:69299
abnormal renal glomerulus morphology J:69299
decreased circulating cholesterol level J:69299
decreased circulating HDL cholesterol level J:69299
decreased circulating VLDL cholesterol level J:69299
expanded mesangial matrix J:69299
glomerulosclerosis J:69299
normal hematopoietic system phenotype J:69299
hemolytic anemia J:69299
normal homeostasis/metabolism phenotype J:69299
increased circulating triglyceride level J:69299
increased urine protein level J:69299
mesangial cell hyperplasia J:69299
reticulocytosis J:69299
normal vision/eye phenotype J:69299
Lcattm1Nsa/Lcattm1Nsa
involves: 129X1/SvJ * C57BL/6J
abnormal cholesterol homeostasis J:39237
abnormal lipid level J:39237
decreased circulating cholesterol level J:39237
decreased circulating HDL cholesterol level J:39237
increased circulating triglyceride level J:39237
normal renal/urinary system phenotype J:39237
normal vision/eye phenotype J:39237
Tg(Lcat)1Ssf/Tg(Lcat)1Ssf
C57BL/6-Tg(Lcat)1Ssf
increased circulating cholesterol level J:94077
increased circulating HDL cholesterol level J:94077
increased circulating phospholipid level J:94077

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory