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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Itgb6
integrin beta 6
MGI:96615
27 phenotypes from 2 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Itgb6em1(IMPC)Ccpcz/Itgb6em1(IMPC)Ccpcz
C57BL/6NCrl-Itgb6em1(IMPC)Ccpcz/Ccpcz
abnormal digit morphology J:211773
abnormal eye morphology J:211773
abnormal skin morphology J:211773
abnormal thymus morphology J:211773
abnormal tooth color J:211773
abnormal tooth morphology J:211773
anophthalmia J:211773
decreased body weight J:211773
decreased lung elastance J:211773
decreased lung tissue damping J:211773
decreased respiratory quotient J:211773
enlarged thymus J:211773
increased freezing behavior J:211773
increased lung compliance J:211773
preweaning lethality, incomplete penetrance J:211773
Itgb6tm1Des/Itgb6tm1Des
either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6)
abnormal response/metabolism to endogenous compounds J:109367
decreased susceptibility to injury J:109367
Itgb6tm1Des/Itgb6tm1Des
involves: 129S4/SvJae
abnormal immune system physiology J:120085
absent Langerhans cell J:120085
decreased Langerhans cell number J:120085
Itgb6tm1Des/Itgb6tm1Des
involves: 129S4/SvJae * C57BL/6 * SJL
respiratory system inflammation J:51592
Itgb6tm1Des/Itgb6tm1Des
involves: 129S4/SvJae * C57BL/6J
abnormal hair follicle morphology J:33139
abnormal lung morphology J:33139
alopecia J:33139
decreased hair follicle number J:33139
respiratory system inflammation J:33139
Itgb6tm1Des/Itgb6tm1Des
involves: 129T2/SvEms
emphysema J:89578
overexpanded pulmonary alveolus J:89578

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory