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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Itga6
integrin alpha 6
MGI:96605
35 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Itga3tm1Hap/Itga3tm1Hap
Itga6tm2Egl/Itga6tm2Egl
Tg(Mpz-cre)26Mes/0
involves: 129 * C57BL/6 * FVB/NTac
normal nervous system phenotype J:204174
Itga3tm1Jak/Itga3tm1Jak
Itga6tm1Egl/Itga6tm1Egl
involves: 129S2/SvPas * 129S4/SvJae
abnormal apical ectodermal ridge morphology J:56564
abnormal autopod morphology J:56564
abnormal choroid plexus morphology J:56564
abnormal digit development J:56564
abnormal epidermal layer morphology J:56564
abnormal left lung morphology J:56564
abnormal lens epithelium morphology J:56564
abnormal Mullerian duct morphology J:56564
abnormal neural tube closure J:56564
abnormal primitive urogenital sinus morphology J:56564
abnormal rectum morphology J:56564
abnormal retinal nerve fiber layer morphology J:56564
abnormal right lung morphology J:56564
abnormal stratification in cerebral cortex J:56564
abnormal vitreous body morphology J:56564
abnormal Wolffian duct morphology J:56564
absent ureter J:56564
absent urinary bladder J:56564
disorganized retinal ganglion layer J:56564
fetal growth retardation J:56564
impaired branching involved in terminal bronchiole morphogenesis J:56564
impaired lung lobe morphogenesis J:56564
lethality throughout fetal growth and development, complete penetrance J:56564
oligodactyly J:56564
pancreas hypoplasia J:56564
pulmonary hypoplasia J:56564
syndactyly J:56564
urethra atresia J:56564
Itga6tm2Egl/Itga6tm2Egl
Itga7tm1Umr/Itga7tm1Umr
Tg(Mpz-cre)26Mes/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/NTac
abnormal axon radial sorting J:204174
abnormal myelination J:204174
abnormal Schwann cell physiology J:204174
abnormal sciatic nerve morphology J:204174
axon degeneration J:204174
hypermyelination J:204174

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory