Itga1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itga1
integrin alpha 1
MGI:96599

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Col4a3^tm1Dec/Col4a3^tm1Dec Itga1^tm1Gdnr/Itga1^tm1Gdnr involves: 129S4/SvJae * 129X1/SvJ * BALB/c	abnormal kidney morphology	J:71378
	abnormal renal glomerulus basement membrane morphology	J:91620
	increased circulating total protein level	J:91620
	kidney failure	J:91620
	tubular nephritis	J:71378
Ins2^Akita/Ins2^Akita Itga1^tm1Gdnr/Itga1^tm1Gdnr C.Cg-Ins2^Akita Itga1^tm1Gdnr	abnormal glomerular capillary morphology	J:198186
	abnormal glomerular mesangium morphology	J:198186
	abnormal kidney interstitium morphology	J:198186
	albuminuria	J:198186
	decreased body weight	J:198186
	expanded mesangial matrix	J:198186
	glomerulosclerosis	J:198186
	hyperglycemia	J:198186
	increased renal glomerular filtration rate	J:198186
	increased renal glomerulus basement membrane thickness	J:198186
	mesangiolysis	J:198186
	premature death	J:198186
	renal glomerular protein deposits	J:198186

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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