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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Impdh1
inosine monophosphate dehydrogenase 1
MGI:96567
7 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Hprtb-m3/Y
Impdh1tm1Bmi/Impdh1tm1Bmi
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal lymphopoiesis J:85443
decreased cytotoxic T cell cytolysis J:85443
decreased interleukin-4 secretion J:85443
decreased splenocyte proliferation J:85443
decreased T cell proliferation J:85443
Impdh1tm1Bmi/Impdh1tm1Bmi
Impdh2tm1Bmi/Impdh2+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal cytotoxic T cell physiology J:85443
abnormal immune system cell morphology J:85443
abnormal lymphopoiesis J:85443
decreased splenocyte proliferation J:85443
decreased T cell proliferation J:85443

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory