Igl Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Igl
immunoglobulin lambda chain complex
MGI:96526

14 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ighm^tm1Cgn/Ighm^tm1Cgn Igkc^tm1Bgmn/Igkc^tm1Bgmn Igl^tm2.1Bgmn/Igl^tm2.1Bgmn involves: 129	decreased IgG level	J:130864
	decreased IgM level	J:130864
Ighm^tm3Bgmn/Ighm^tm3Bgmn Igkc^tm1Bgmn/Igkc^tm1Bgmn Igl^tm2.1Bgmn/Igl^tm2.1Bgmn involves: 129P2/OlaHsd * 129/Sv	abnormal B cell differentiation	J:130864
	decreased IgG level	J:130864
	decreased IgM level	J:130864
Igkc^tm1Bgmn/Igkc^tm1Bgmn Igl^tm1.1Bgmn/Igl^tm1.1Bgmn involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA	abnormal immature B cell morphology	J:118712
	absent B cells	J:118712
	absent B-1 B cells	J:118712
	absent B-2 B cells	J:118712
	decreased B cell number	J:118712
	spleen hypoplasia	J:118712
Igkc^tm1Bgmn/Igkc^tm1Bgmn Igl^tm1Bgmn/Igl^tm1Bgmn involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA	abnormal immature B cell morphology	J:118712
	absent B-1 B cells	J:118712
	absent B-2 B cells	J:118712
	absent mature B cells	J:118712
	decreased B cell number	J:118712
	spleen hypoplasia	J:118712
Igkc^tm1Bgmn/Igkc^tm1Bgmn Igl^tm2.1Bgmn/Igl^tm2.1Bgmn involves: 129P2/OlaHsd	abnormal B cell differentiation	J:130864
	abnormal immunoglobulin heavy chain V(D)J recombination	J:130864
	abnormal plasma cell morphology	J:130864
	decreased IgG level	J:130864
	decreased IgM level	J:130864
Igkc^tm1Bgmn/Igkc^tm1Bgmn Igl^tm2.1Bgmn/Igl^tm2.1Bgmn involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA	absent B cells	J:118712
	arrested B cell differentiation	J:118712
Igkc^tm1Bgmn/Igkc^tm1Bgmn Igl^tm2Bgmn/Igl^tm2Bgmn involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA	absent B cells	J:118712
	arrested B cell differentiation	J:118712
Igl^tm1Cgn/Igl^tm1Cgn involves: C57BL/6	normal immune system phenotype	J:83289

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23