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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Igh-8
immunoglobulin heavy chain 8 (heavy chain of IgG3)
MGI:96450
6 phenotypes from 5 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Igh-8tm1.1Aak/Igh-8tm1.1Aak
involves: 129S2/SvPas * C57BL/6
abnormal class switch recombination J:171251
Igh-8tm1Aak/Igh-8tm1Aak
involves: 129S2/SvPas * C57BL/6
abnormal class switch recombination J:107063
Igh-8tm1Schr/Igh-8tm1Schr
C.129P2(BKSW)-Igh-8tm1Schr
increased IgG level J:75577
increased IgM level J:75577
increased susceptibility to bacterial infection J:75577
Igh-8tm1Schr/Igh-8tm1Schr
involves: 129P2/OlaHsd * Black Swiss
increased IgM level J:49847
Igh-8tm2(Ighg1)Aak/Igh-8tm2(Ighg1)Aak
involves: 129S2/SvPas
abnormal class switch recombination J:130574
decreased IgG3 level J:130574
Igh-8tm2.1Aak/Igh-8tm2.1Aak
involves: 129S2/SvPas * C57BL/6
normal immune system phenotype J:171251

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory