Idh2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Idh2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
MGI:96414

19 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Idh2^{tm1b(EUCOMM)Hmgu}/Idh2^{tm1b(EUCOMM)Hmgu} C57BL/6N-Idh2^{tm1b(EUCOMM)Hmgu}/H	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular volume	J:211773
	increased hemoglobin content	J:211773
Idh2^tm1Jwpk/Idh2^tm1Jwpk involves: 129S4/SvJae * C57BL/6	abnormal spine curvature	J:272241
	abnormal trabecular bone morphology	J:272241
	abnormal tumor pathology	J:210036
	abnormal tumor vascularization	J:210036
	abnormal vertebral body morphology	J:272241
	abnormal vertebral column morphology	J:272241
	decreased bone mineral density	J:272241
	decreased bone trabecula number	J:272241
	decreased osteoblast cell number	J:272241
	decreased trabecular bone thickness	J:272241
	decreased trabecular bone volume	J:272241
	decreased tumor growth/size	J:210036
	increased bone trabecular spacing	J:272241
	increased osteoclast cell number	J:272241
	kyphosis	J:272241
	oxidative stress	J:272241

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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