45 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Hoxa1tm1Ipc/Hoxa1tm1Ipc Hoxb1tm1Ipc/Hoxb1tm1Ipc involves: 129S2/SvPas * 129S7/SvEvBrd	abnormal neural crest cell delamination	J:71033
	abnormal neural crest cell migration	J:71033
	normal embryo phenotype	J:71033
	normal muscle phenotype	J:124278
Hoxa1tm1Mrc/Hoxa1tm2Mrc Hoxa2tm1Mrc/Hoxa2+ involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ	abnormal basioccipital bone morphology	J:58093
	abnormal cranium morphology	J:58093
	absent stapes	J:58093
	neonatal lethality, complete penetrance	J:58093
	respiratory failure	J:58093
	small ears	J:58093
	small middle ear ossicles	J:58093
Hoxa1tm2Mrc/Hoxa1+ Hoxa2tm1Mrc/Hoxa2+ involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:58093
Hoxa1tm2Mrc/Hoxa1+ Hoxa2tm1Mrc/Hoxa2tm1Mrc involves: 129S1/Sv * 129X1/SvJ	abnormal suckling behavior	J:58093
	cleft secondary palate	J:58093
	neonatal lethality, complete penetrance	J:58093
Hoxa1tm2Mrc/Hoxa1tm2Mrc Hoxa2tm1Mrc/Hoxa2tm1Mrc involves: 129S1/Sv * 129X1/SvJ	abnormal hindbrain morphology	J:58093
	abnormal middle ear ossicle morphology	J:58093
	absent outer ear	J:58093
	neonatal lethality, complete penetrance	J:58093
	small middle ear ossicles	J:58093
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc Hoxb1tm3Mrc/Hoxb1+ involves: 129S1/Sv * 129X1/SvJ	abnormal neural crest cell migration	J:41540
	abnormal neuron differentiation	J:41540
	abnormal pharyngeal pouch morphology	J:41540
	abnormal rhombomere morphology	J:41540
	absent parathyroid glands	J:41540
	absent second pharyngeal arch	J:41540
	small thymus	J:41540
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc Hoxb1tm3Mrc/Hoxb1tm3Mrc involves: 129S1/Sv * 129X1/SvJ	abnormal digastric posterior belly morphology	J:41540
	abnormal neural crest cell migration	J:41540
	abnormal neuron differentiation	J:41540
	abnormal rhombomere morphology	J:41540
	abnormal stylohyoid muscle morphology	J:41540
	abnormal third pharyngeal pouch morphology	J:41540
	absent facial muscle	J:41540
	absent levator labii superioris muscle	J:41540
	absent orbicularis oculi muscle	J:41540
	absent parathyroid glands	J:41540
	absent rhombomere 4	J:41540
	absent rhombomere 5	J:41540
	absent second pharyngeal arch	J:41540
	absent second pharyngeal pouch	J:41540
	absent stapes	J:41540
	absent zygomaticus muscle	J:41540
	athymia	J:41540
	increased hindbrain apoptosis	J:41540
	pulmonary hypoplasia	J:41540
	small incus	J:41540
	small malleus	J:41540
Hoxa1tm3.1Mrc/Hoxa1tm4(Hoxb1)Mrc Hoxb1tm5Mrc/Hoxb1tm8(Hoxa1)Mrc involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6	abnormal blinking	J:119279
	facial paralysis	J:119279
Hoxa1tm4(Hoxb1)Mrc/Hoxa1tm4(Hoxb1)Mrc Hoxb1tm5Mrc/Hoxb1tm8(Hoxa1)Mrc involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6	abnormal facial nerve morphology	J:119279
	abnormal reflex	J:119279
Hoxa1tm4(Hoxb1)Mrc/Hoxa1tm4(Hoxb1)Mrc Hoxb1tm8(Hoxa1)Mrc/Hoxb1tm8(Hoxa1)Mrc involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6	no abnormal phenotype detected	J:119279
Hoxa1tm5Mrc/Hoxa1+ Hoxb1tm5Mrc/Hoxb1tm5Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal facial nerve morphology	J:119279
	abnormal reflex	J:119279
	paralysis	J:119279
	small facial motor nucleus	J:119279
Hoxa1tm5Mrc/Hoxa1tm5Mrc Hoxb1tm5Mrc/Hoxb1tm5Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal nervous system phenotype	J:119279