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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hoxa1
homeobox A1
MGI:96170
45 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Hoxa1tm1Ipc/Hoxa1tm1Ipc
Hoxb1tm1Ipc/Hoxb1tm1Ipc
involves: 129S2/SvPas * 129S7/SvEvBrd
abnormal neural crest cell delamination J:71033
abnormal neural crest cell migration J:71033
normal embryo phenotype J:71033
normal muscle phenotype J:124278
Hoxa1tm1Mrc/Hoxa1tm2Mrc
Hoxa2tm1Mrc/Hoxa2+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
abnormal basioccipital bone morphology J:58093
abnormal cranium morphology J:58093
absent stapes J:58093
neonatal lethality, complete penetrance J:58093
respiratory failure J:58093
small ears J:58093
small middle ear ossicles J:58093
Hoxa1tm2Mrc/Hoxa1+
Hoxa2tm1Mrc/Hoxa2+
involves: 129S1/Sv * 129X1/SvJ
no abnormal phenotype detected J:58093
Hoxa1tm2Mrc/Hoxa1+
Hoxa2tm1Mrc/Hoxa2tm1Mrc
involves: 129S1/Sv * 129X1/SvJ
abnormal suckling behavior J:58093
cleft secondary palate J:58093
neonatal lethality, complete penetrance J:58093
Hoxa1tm2Mrc/Hoxa1tm2Mrc
Hoxa2tm1Mrc/Hoxa2tm1Mrc
involves: 129S1/Sv * 129X1/SvJ
abnormal hindbrain morphology J:58093
abnormal middle ear ossicle morphology J:58093
absent outer ear J:58093
neonatal lethality, complete penetrance J:58093
small middle ear ossicles J:58093
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc
Hoxb1tm3Mrc/Hoxb1+
involves: 129S1/Sv * 129X1/SvJ
abnormal neural crest cell migration J:41540
abnormal neuron differentiation J:41540
abnormal pharyngeal pouch morphology J:41540
abnormal rhombomere morphology J:41540
absent parathyroid glands J:41540
absent second pharyngeal arch J:41540
small thymus J:41540
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc
Hoxb1tm3Mrc/Hoxb1tm3Mrc
involves: 129S1/Sv * 129X1/SvJ
abnormal digastric posterior belly morphology J:41540
abnormal neural crest cell migration J:41540
abnormal neuron differentiation J:41540
abnormal rhombomere morphology J:41540
abnormal stylohyoid muscle morphology J:41540
abnormal third pharyngeal pouch morphology J:41540
absent facial muscle J:41540
absent levator labii superioris muscle J:41540
absent orbicularis oculi muscle J:41540
absent parathyroid glands J:41540
absent rhombomere 4 J:41540
absent rhombomere 5 J:41540
absent second pharyngeal arch J:41540
absent second pharyngeal pouch J:41540
absent stapes J:41540
absent zygomaticus muscle J:41540
athymia J:41540
increased hindbrain apoptosis J:41540
pulmonary hypoplasia J:41540
small incus J:41540
small malleus J:41540
Hoxa1tm3.1Mrc/Hoxa1tm4(Hoxb1)Mrc
Hoxb1tm5Mrc/Hoxb1tm8(Hoxa1)Mrc
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
abnormal blinking J:119279
facial paralysis J:119279
Hoxa1tm4(Hoxb1)Mrc/Hoxa1tm4(Hoxb1)Mrc
Hoxb1tm5Mrc/Hoxb1tm8(Hoxa1)Mrc
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
abnormal facial nerve morphology J:119279
abnormal reflex J:119279
Hoxa1tm4(Hoxb1)Mrc/Hoxa1tm4(Hoxb1)Mrc
Hoxb1tm8(Hoxa1)Mrc/Hoxb1tm8(Hoxa1)Mrc
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
no abnormal phenotype detected J:119279
Hoxa1tm5Mrc/Hoxa1+
Hoxb1tm5Mrc/Hoxb1tm5Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal facial nerve morphology J:119279
abnormal reflex J:119279
paralysis J:119279
small facial motor nucleus J:119279
Hoxa1tm5Mrc/Hoxa1tm5Mrc
Hoxb1tm5Mrc/Hoxb1tm5Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
normal nervous system phenotype J:119279

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory