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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hmox1
heme oxygenase 1
MGI:96163
38 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Ak7Tg(tetO-Hmox1)67Sami/Ak7Tg(tetO-Hmox1)67Sami
FVB/N-Ak7Tg(tetO-Hmox1)67Sami
abnormal cerebellum morphology J:186062
abnormal respiratory motile cilium morphology J:186062
abnormal respiratory motile cilium physiology J:186062
abnormal sperm head morphology J:186062
azoospermia J:186062
enlarged lateral ventricles J:186062
normal growth/size/body region phenotype J:186062
hydrocephaly J:186062
male infertility J:186062
postnatal growth retardation J:186062
premature death J:186062
normal renal/urinary system phenotype J:186062
normal reproductive system phenotype J:186062
respiratory system inflammation J:186062
rhinitis J:186062
thin cerebral cortex J:186062
Hmox1tm1Poss/Hmox1tm1Poss
Spictm2Kmm/Spictm2Kmm
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * FVB/N
decreased macrophage cell number J:210804
Tg(Eno2-Hmox1)2Main/Tg(Eno2-Hmox1)2Main
involves: C57BL/6J
circling J:120240
decreased exploration in new environment J:120240
enlarged spleen J:120240
Tg(GFAP-tTA)6Hyms/0
Tg(tetO-HMOX1)6Hyms/0
involves: FVB/N
abnormal astrocyte morphology J:186620, J:190573
abnormal autophagy J:186620, J:190573
abnormal dentate gyrus morphology J:186620
abnormal hippocampus morphology J:186620
abnormal mitochondrial crista morphology J:186620, J:190573
abnormal mitochondrial inner membrane morphology J:190573
abnormal mitochondrion morphology J:186620, J:190573
abnormal nervous system physiology J:186620
abnormal neurite morphology J:186620, J:190573
abnormal striatum morphology J:186620
abnormal substantia nigra morphology J:186620
decreased prepulse inhibition J:186620
disorganized mitochondrial cristae J:186620
hyperactivity J:186620
increased brain iron level J:186620, J:190573
increased dopamine level J:186620
increased serotonin level J:186620
oxidative stress J:186620, J:190573

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory