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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hdc
histidine decarboxylase
MGI:96062
30 phenotypes from 1 allele in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Hdctm1Nagy/Hdc+
involves: 129S1/Sv * 129X1/SvJ
abnormal behavioral response to amphetamine J:220412
abnormal striatum morphology J:220412
abnormal substantia nigra morphology J:220412
normal behavior/neurological phenotype J:220412
decreased prepulse inhibition J:220412
Hdctm1Nagy/Hdctm1Nagy
B6.129-Hdctm1Nagy
abnormal learning/memory/conditioning J:105032, J:106034
abnormal passive avoidance behavior J:106034
abnormal spatial learning J:105032
decreased exploration in new environment J:105032
increased anxiety-related response J:105032, J:106034
Hdctm1Nagy/Hdctm1Nagy
involves: 129S1/Sv * 129X1/SvJ
abnormal behavioral response to amphetamine J:220412
abnormal mast cell morphology J:70702
abnormal mechanical nociception J:106399
abnormal striatum morphology J:220412
abnormal substantia nigra morphology J:220412
normal behavior/neurological phenotype J:220412
decreased mast cell histamine storage J:70702
decreased mast cell number J:70702
decreased mast cell protease storage J:70702
decreased prepulse inhibition J:220412
increased chemical nociceptive threshold J:106399
increased dopamine level J:220412
increased thermal nociceptive threshold J:106399
Hdctm1Nagy/Hdctm1Nagy
involves: 129S1/Sv * 129X1/SvJ * CD-1
abnormal brain morphology J:85774
abnormal energy expenditure J:85774
impaired glucose tolerance J:85774
increased brown adipose tissue amount J:85774
increased circulating insulin level J:85774
increased circulating leptin level J:85774
increased epididymal fat pad weight J:85774
increased interscapular fat pad weight J:85774
increased susceptibility to weight gain J:85774
increased white adipose tissue amount J:85774
increased white fat cell size J:85774
obese J:85774

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory