H2-K1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

H2-K1
histocompatibility 2, K1, K region
MGI:95904

21 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
H2-Ab1^g7-em1Dvs/H2-Ab1^g7-em1Dvs H2-D1^b-em5Dvs/H2-D1^b-em5Dvs H2-K1^d-em1Dvs/H2-K1^d-em1Dvs NOD/ShiLtDvs-H2-K1^d-em1Dvs H2-Ab1^g7-em1Dvs H2-D1^em5Dvs/Dvs	abnormal T cell subpopulation ratio	J:257229
	decreased alpha-beta T cell number	J:257229
	decreased CD4-positive, alpha-beta T cell number	J:257229
	decreased susceptibility to autoimmune diabetes	J:257229
H2-D1^b-em5Dvs/H2-D1^b-em5Dvs H2-K1^d-em1Dvs/H2-K1^d-em1Dvs NOD/ShiLtDvs-H2-K1^d-em1Dvs H2-D1^b-em5Dvs/Dvs	abnormal T cell subpopulation ratio	J:257229
	decreased susceptibility to autoimmune diabetes	J:257229
H2-D1^b-em5Dvs/H2-D1^b-em5Dvs H2-K1^d-em1Dvs/H2-K1^d-em1Dvs Tg(HLA-A/H2-D/B2M)1Dvs/? NOD/ShiLtDvs-H2-K1^d-em1Dvs H2-D1^b-em5Dvs Tg(HLA-A/H2-D/B2M)1Dvs/Dvs	autoimmune response	J:257229
	increased susceptibility to autoimmune diabetes	J:257229
	insulitis	J:257229
H2-D1^b-em5Dvs/H2-D1^b-em5Dvs H2-K1^d-em1Dvs/H2-K1^d-em1Dvs Tg(HLA-B39/H2-D/B2m)2Dvs/? NOD/ShiLtDvs-H2-K1^d-em1Dvs H2-D1^b-em5Dvs Tg(HLA-B39/H2-D/B2M)2Dvs/Dvs	autoimmune response	J:257229
	increased susceptibility to autoimmune diabetes	J:257229
	insulitis	J:257229
H2-D1^b-tm1Bpe/H2-D1^b-tm1Bpe H2-K1^b-tm1Bpe/H2-K1^b-tm1Bpe B6.129P-H2-D1^b-tm1Bpe H2-K1^b-tm1Bpe	abnormal cytotoxic T cell physiology	J:118960
H2-D1^b-tm1Bpe/H2-D1^b-tm1Bpe H2-K1^b-tm1Bpe/H2-K1^b-tm1Bpe involves: 129P2/OlaHsd * C57BL/6	abnormal glutamate-mediated receptor currents	J:148342
	absent CD8-positive, alpha-beta T cells	J:57703
	decreased CD8-positive, alpha-beta T cell number	J:54709
	decreased susceptibility to Riboviria infection induced morbidity/mortality	J:54709
	enhanced coordination	J:148342
	enhanced paired-pulse facilitation	J:148342
	increased CD4-positive, alpha-beta T cell number	J:54709
	increased synaptic depression	J:148342
	normal nervous system phenotype	J:148342
H2-D1^b-tm1Bpe/H2-D1^b-tm1Bpe H2-K1^b-tm1Bpe/H2-K1^b-tm1Bpe Klra1^tm1.1Wyok/Klra1^tm1.1Wyok involves: 129P2/OlaHsd * BALB/cJ * C57BL/6NTac	normal hematopoietic system phenotype	J:252851
H2-D1^b-tm1Bpe/H2-D1^b-tm1Bpe H2-K1^b-tm1Bpe/H2-K1^b-tm1Bpe Klra1^tm1.1Wyok/Klra1^tm1.1Wyok Tg(H2-D^d)28Bee/0 involves: 129P2/OlaHsd * BALB/cJ * C57BL/6NTac * DBA/2	abnormal NK cell physiology	J:252851
	normal hematopoietic system phenotype	J:252851
H2-D1^b-tm1Bpe/H2-D1^b-tm1Bpe H2-K1^b-tm1Bpe/H2-K1^b-tm1Bpe X/Yaa BXSB.129P2(B6)-H2-K1^b-tm1Bpe H2-D1^b-tm1Bpe/Dcr	increased susceptibility to systemic lupus erythematosus	J:179430
	premature death	J:179430

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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