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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
MGI:95777
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
ApcMin/Apc+
Gpa33tm1(GNAS)Wtsi/Gpa33+
Hprttm1(CMV-cre)Brd/?
involves: 129S7/SvEvBrd * C57BL/6J
increased intestinal adenoma incidence J:168378
Braftm1Cpri/Braftm1Cpri
Gnastm3Lsw/Gnastm3Lsw
Tg(TPO-cre)1Shk/0
involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/NCr
increased thyroid tumor incidence J:168249
GnasOedsml/Gnas+
Nespastm1Jop/Nespas+
involves: 101/H * 129S/SvEv * C3H/HeH
edema J:106793
Gnastm5Lsw/Gnastm5Lsw
Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+
Olfr151tm28(cre)Mom/Olfr151tm27Mom
involves: 129P2/OlaHsd * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
normal taste/olfaction phenotype J:233447
Gnastm5Lsw/Gnastm5Lsw
Tg(Gfy-cre)1Yyos/?
involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * FVB/N
normal taste/olfaction phenotype J:233447
Gpa33tm1(GNAS)Wtsi/Gpa33+
Hprttm1(CMV-cre)Brd/?
involves: 129S7/SvEvBrd * C57BL/6J
normal digestive/alimentary phenotype J:168378
Olfr151tm37(Olfr16*,Gnas*)Mom/Olfr151+
B6;129P2-Olfr151tm37(Olfr16*,Gnas*)Mom/MomJ
abnormal olfactory receptor morphology J:233447
abnormal olfactory sensory neuron morphology J:233447
decreased olfactory sensory neuron number J:233447
impaired olfaction J:233447
Tg(EEF1A1-Gnas*R201C)184Pabi/0
either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * FVB/N)
abnormal bone marrow cavity morphology J:240241
abnormal bone mineralization J:240241
abnormal bone remodeling J:240241
abnormal bone trabecula morphology J:240241
abnormal compact bone morphology J:240241
abnormal skeleton morphology J:240241
exostosis J:240241
fragile skeleton J:240241
increased bone ossification J:240241
increased bone resorption J:240241
increased internal diameter of femur J:240241
osteosclerosis J:240241
Tg(PGK1-Gnas*R201C)60Pabi/0
either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * FVB/N)
abnormal skeleton morphology J:240241
fragile skeleton J:240241

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory