Gdf5 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gdf5
growth differentiation factor 5
MGI:95688

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bmpr1b^{Tg(ACTB-FLP)4917Dym}/Bmpr1b^{Tg(ACTB-FLP)4917Dym} Gdf5^bp-J/Gdf5^bp-J involves: A/J * C57BL/6 * SJL	abnormal cartilage development	J:59288
	abnormal digit morphology	J:59288
	abnormal metacarpal bone morphology	J:59288
	abnormal metatarsal bone morphology	J:59288
Bmpr1b^tm1Kml/Bmpr1b⁺ Gdf5^bp-J/Gdf5⁺ involves: 129S/SvEv * A/J * C57BL/6J	abnormal phalanx morphology	J:59282
	delayed bone ossification	J:59282
Bmpr1b^tm1Kml/Bmpr1b^tm1Kml Gdf5^bp-J/Gdf5^bp-J involves: 129S/SvEv * A/J * C57BL/6J	abnormal limb morphology	J:59282
	fused metacarpal bones	J:59282
	fused metatarsal bones	J:59282
	short metacarpal bones	J:59282
Gdf5^bp-J/Gdf5^bp-J Gdf6^tm1Kng/Gdf6^tm1Kng involves: 129S1/Sv * 129X1/SvJ * A/J * C57BL/6J	abnormal carpal bone morphology	J:83132
	abnormal metatarsal bone morphology	J:83132
	abnormal phalanx morphology	J:83132
	abnormal vertebral articular process morphology	J:83132
	abnormal vertebral spinous process morphology	J:83132
	absent talus	J:83132
	bowed radius	J:83132
	delayed bone ossification	J:83132
	fused joints	J:83132
	premature death	J:83132
	scoliosis	J:83132
	short ulna	J:83132

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23