70 phenotypes from 5 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gabrb3tm1Geh/Gabrb3tm1Geh involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal auditory brainstem response waveform shape	J:112951
	abnormal CNS synaptic transmission	J:39801
	abnormal cochlea morphology	J:112951
	abnormal cochlear IHC afferent innervation pattern	J:112951
	abnormal cochlear nerve morphology	J:112951
	abnormal cochlear OHC efferent innervation pattern	J:112951
	abnormal motor capabilities/coordination/movement	J:39801
	abnormal parental behavior	J:39801
	circling	J:39801, J:108890
	cleft palate	J:39801
	cochlear ganglion degeneration	J:112951
	cochlear ganglion hypoplasia	J:108890
	cochlear inner hair cell degeneration	J:112951
	cochlear outer hair cell degeneration	J:112951
	decreased body size	J:39801
	hyperactivity	J:39801
	hyperresponsive	J:39801
	impaired coordination	J:39801
	impaired swimming	J:39801
	increased or absent distortion product otoacoustic emission threshold	J:112951
	increased or absent threshold for auditory brainstem response	J:112951
	limb grasping	J:39801
	perinatal lethality, incomplete penetrance	J:39801
	premature death	J:39801
	seizures	J:39801
	sensorineural hearing loss	J:112951
	small cochlear ganglion	J:108890
	small vestibular ganglion	J:108890
	type IV spiral ligament fibrocyte degeneration	J:112951
	vestibular ganglion hypoplasia	J:108890
Gabrb3tm1Geh/Gabrb3tm1Geh involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal behavior	J:130259
	abnormal cerebellum vermis lobule II morphology	J:130259
	abnormal cerebellum vermis lobule III morphology	J:130259
	abnormal cerebellum vermis lobule IV morphology	J:130259
	abnormal cerebellum vermis lobule morphology	J:130259
	abnormal cerebellum vermis lobule V morphology	J:130259
	abnormal cerebellum vermis lobule VI morphology	J:130259
	abnormal cerebellum vermis lobule VII morphology	J:130259
	abnormal nest building behavior	J:130259
	abnormal response to novel object	J:130259
	abnormal social/conspecific interaction behavior	J:130259
	circling	J:130259
	decreased vertical activity	J:130259
	increased locomotor activity	J:130259
Gabrb3tm1Uru/Gabrb3tm1Uru involves: 129X1/SvJ * C57BL/6J	abnormal action potential	J:81497, J:105539
	abnormal CNS synaptic transmission	J:105539
	abnormal GABA-mediated receptor currents	J:81497
	abnormal reflex	J:81497
	abnormal righting response	J:81497
	normal behavior/neurological phenotype	J:81497
	impaired behavioral response to xenobiotic	J:81497
	tremors	J:81497
Gabrb3tm2.1Geh/Gabrb3tm2.1Geh involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	no abnormal phenotype detected	J:127877
Gabrb3tm2.1Geh/Gabrb3tm2.1Geh Tg(Camk2a-cre)T29-1Stl/? involves: 129 * BALB/c * C57BL/6 * SJL	abnormal behavior	J:127877
	abnormal maternal nurturing	J:127877
	absence seizures	J:127877
	hyperactivity	J:127877
	impaired behavioral response to xenobiotic	J:127877
	increased food intake	J:127877
	obese	J:127877
	postnatal lethality, incomplete penetrance	J:127877
	reduced female fertility	J:127877
	reduced male fertility	J:127877
	reduced male mating frequency	J:127877
Gabrb3tm2.1Geh/Gabrb3tm2.1Geh Tg(Syn1-cre)671Jxm/? involves: 129 * C57BL/6 * CBA * SJL	normal behavior/neurological phenotype	J:127877
	impaired behavioral response to xenobiotic	J:127877
	postnatal lethality, incomplete penetrance	J:127877
Gabrb3tm2.1Uru/Gabrb3tm2.1Uru B6J.129S6(Cg)-Gabrb3tm2.1Uru	abnormal CNS synaptic transmission	J:228332
	abnormal dentate gyrus neuron dendrite morphology	J:228332
	abnormal hippocampus neuron morphology	J:228332
	abnormal inhibitory postsynaptic potential	J:228332
	abnormal response to social novelty	J:228332
	normal behavior/neurological phenotype	J:228332
	enhanced contextual conditioning behavior	J:228332
	increased excitatory postsynaptic current amplitude	J:228332
	increased stereotypic behavior	J:228332
	increased susceptibility to pharmacologically induced seizures	J:228332
	prolonged excitatory postsynaptic current decay time	J:228332
Gabrb3tm2.2Geh/Gabrb3tm2.2Geh involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL	cleft palate	J:127877
	lethality at weaning, complete penetrance	J:127877
	neonatal lethality, incomplete penetrance	J:127877