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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
En2
engrailed 2
MGI:95390
31 phenotypes from 6 alleles in 9 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
En2tm1Alj/En2+
either: (involves: 129S2/SvPas * 129/Sv) or (involves: 129S2/SvPas * C57BL/6) or (involves: 129S2/SvPas * CD-1)
abnormal behavior J:31921
En2tm1Alj/En2tm1Alj
either: (involves: 129S2/SvPas * 129/Sv) or (involves: 129S2/SvPas * C57BL/6) or (involves: 129S2/SvPas * CD-1)
abnormal cerebellar foliation J:31921, J:67524
abnormal cerebellum development J:67524
abnormal cerebellum posterior vermis morphology J:31921
abnormal cerebellum vermis morphology J:67524
abnormal locomotor activation J:31921
impaired coordination J:31921
increased defecation amount J:31921
small cerebellum J:31921, J:67524
En2tm1Alj/En2tm1Alj
involves: 129/Sv * 129S2/SvPas
abnormal cerebellar foliation J:17203
abnormal cerebellar granule layer morphology J:17203
abnormal cerebellum development J:17203
abnormal cerebellum morphology J:17203
abnormal cerebellum posterior vermis morphology J:17203
decreased colliculi size J:17203
thin external granule cell layer J:17203
En2tm1Alj/En2tm1Alj
involves: 129S2/SvPas * C57BL/6
abnormal grip strength J:114464
abnormal grooming behavior J:114464
abnormal motor capabilities/coordination/movement J:114464
abnormal motor coordination/balance J:114464
abnormal social investigation J:114464
abnormal social/conspecific interaction behavior J:114464
abnormal spatial learning J:114464
decreased aggression towards mice J:114464
decreased grooming behavior J:114464
hyperactivity J:114464
impaired coordination J:114464
impaired righting response J:114464
increased grooming behavior J:114464
increased serotonin level J:114464
En2tm1Alj/En2tm6Alj
Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+
involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster
abnormal cerebellar foliation J:156169
abnormal cerebellum hemisphere lobule morphology J:156169
abnormal cerebellum vermis lobule morphology J:156169
En2tm2Alj/En2tm2Alj
involves: 129S2/SvPas * C57BL/6
abnormal cerebellar foliation J:17203
abnormal cerebellum development J:17203
abnormal cerebellum posterior vermis morphology J:17203
small cerebellum J:17203
En2tm2Alj/En2tm2Alj
involves: 129S2/SvPas * Swiss Webster
abnormal cerebellum morphology J:134516
abnormal cerebellum posterior vermis morphology J:134516
abnormal cerebellum vermis morphology J:134516
decreased inferior colliculus size J:134516
small cerebellum J:134516
En2tm2Alj/En2tm3Alj
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6
normal nervous system phenotype J:60433
En2tm3.1Alj/En2tm3.1Alj
involves: 129S6/SvEvTac
normal nervous system phenotype J:60433
En2tm3Alj/En2tm3Alj
involves: 129S6/SvEvTac
normal nervous system phenotype J:60433
En2tm5.1Alj/En2tm5.1Alj
involves: 129S6/SvEvTac * Black Swiss * Swiss Webster
reduced fertility J:134516
En2tm5.1Alj/En2tm5.1Alj
involves: 129S6/SvEvTac * Swiss Webster
abnormal cerebellar foliation J:156169
abnormal cerebellum hemisphere lobule morphology J:156169
abnormal cerebellum vermis lobule morphology J:156169
En2tm5.1Alj/En2tm5.1Alj
Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+
involves: 129S2/SvPas * Swiss Webster
normal nervous system phenotype J:156169

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory