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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Drd3
dopamine receptor D3
MGI:94925
35 phenotypes from 3 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Drd3tm1Dac/Drd3+
involves: 129S4/SvJae * C57BL/6
abnormal locomotor activation J:96229
decreased grooming behavior J:32128
hyperactivity J:32128, J:96229
increased exploration in new environment J:32128
increased renin activity J:115136
increased systemic arterial diastolic blood pressure J:115136
increased systemic arterial systolic blood pressure J:115136
increased vertical activity J:32128, J:96229
Drd3tm1Dac/Drd3+
involves: 129S4/SvJae * C57BL/6J
decreased anxiety-related response J:44685
Drd3tm1Dac/Drd3tm1Dac
B6.129S4-Drd3tm1Dac
decreased startle reflex J:154428
Drd3tm1Dac/Drd3tm1Dac
B6.129S4-Drd3tm1Dac/J
abnormal motor coordination/ balance J:102600
abnormal physiological response to xenobiotic J:96803
abnormal reflex J:96803
decreased anxiety-related response J:102600
hyperactivity J:102600
increased vertical activity J:102600
Drd3tm1Dac/Drd3tm1Dac
involves: 129S4/SvJae
abnormal behavioral response to addictive substance J:103704
decreased alcohol consumption J:107932
enhanced behavioral response to alcohol J:107932
head bobbing J:103704
hypoactivity J:103704
increased behavioral withdrawal response J:107932
Drd3tm1Dac/Drd3tm1Dac
involves: 129S4/SvJae * C57BL/6
abnormal physiological response to xenobiotic J:115136
decreased grooming behavior J:32128
decreased systemic arterial systolic blood pressure J:115136
decreased urine flow rate J:115136
decreased urine sodium level J:115136
hyperactivity J:32128
impaired behavioral response to morphine J:103701
impaired conditioned place preference behavior J:103701
increased exploration in new environment J:32128
increased renin activity J:115136
increased systemic arterial diastolic blood pressure J:115136
increased systemic arterial systolic blood pressure J:115136
increased vertical activity J:32128
Drd3tm1Dac/Drd3tm1Dac
involves: 129S4/SvJae * C57BL/6J
decreased anxiety-related response J:44685
Drd3tm1Rmw/Drd3tm1Rmw
involves: 129P2/OlaHsd
decreased dopamine level J:117918
increased stereotypic behavior J:117918
Drd3tm1Rmw/Drd3tm1Rmw
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6J
normal behavior/neurological phenotype J:55027
normal nervous system phenotype J:55027
Drd3tm1Stl/Drd3tm1Stl
involves: 129S2/SvPas * C57BL/6
abnormal body water content J:89345
abnormal cued conditioning behavior J:43791
abnormal food intake J:89345
hyperactivity J:43791
increased circulating leptin level J:89345
increased exploration in new environment J:43791
increased percent body fat/body weight J:89345
increased susceptibility to weight gain J:89345
increased total body fat amount J:89345

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory