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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cyp11b2
cytochrome P450, family 11, subfamily b, polypeptide 2
MGI:88584
25 phenotypes from 2 alleles in 1 genetic background
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Allelic Composition
Genetic Background
Annotated Term Reference
Cyp11b2tm1Hsk/Cyp11b2tm1Hsk
involves: 129S6/SvEvTac
abnormal adrenal cortex morphology J:99269
abnormal adrenal gland zona glomerulosa morphology J:99269
abnormal adrenocortical cell morphology J:99269
abnormal enzyme/coenzyme level J:99269
decreased body size J:99269
decreased circulating aldosterone level J:99269
decreased circulating chloride level J:99269
hypotension J:99269
increased circulating corticosterone level J:99269
increased circulating potassium level J:99269
increased circulating renin level J:99269
increased renin activity J:99269
postnatal lethality, incomplete penetrance J:99269
Cyp11b2tm2Hsk/Cyp11b2tm2Hsk
involves: 129S6/SvEvTac
abnormal enzyme/coenzyme activity J:147672
abnormal response/metabolism to endogenous compounds J:147672
cardiac fibrosis J:147672
decreased fluid intake J:147672
decreased urine osmolality J:147672
enlarged myocardial fiber J:147672
hypokalemia J:147672
increased systemic arterial blood pressure J:147672
increased urine osmolality J:147672
oliguria J:147672
oxidative stress J:147672
polyuria J:147672

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory