47 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ctsdm1J/Ctsdm1J C3HeB/FeJ-Ctsdm1J/GrsrJ	abnormal cochlear ganglion morphology	J:229377
	abnormal hair cycle	J:229377
	abnormal intestinal mucosa morphology	J:229377
	abnormal stomach wall morphology	J:229377
	axonal dystrophy	J:229377
	cachexia	J:229377
	deafness	J:229377
	decreased body weight	J:229377
	hippocampal neuron degeneration	J:229377
	increased or absent threshold for auditory brainstem response	J:229377
	lethality at weaning, complete penetrance	J:229377
	neuron degeneration	J:229377
	prenatal lethality, incomplete penetrance	J:229377
	preweaning lethality, incomplete penetrance	J:229377
	thymus atrophy	J:229377
	weakness	J:229377
Ctsdtm1.1Thre/Ctsdtm1.1Thre Edil3Tg(Sox2-cre)1Amc/Edil3+ involves: C57BL/6 * C57BL/6N * CBA * SJL	astrocytosis	J:227618
	decreased body weight	J:227618
	decreased double-positive T cell number	J:227618
	decreased small intestinal villus height	J:227618
	gliosis	J:227618
	microgliosis	J:227618
	neuron degeneration	J:227618
	premature death	J:227618
	small intestinal villus atrophy	J:227618
	thymus atrophy	J:227618
	weight loss	J:227618
Ctsdtm1.1Thre/Ctsdtm1.1Thre Tg(Nes-cre)1Kln/0 involves: C57BL/6 * C57BL/6N * SJL	abnormal thymus morphology	J:227618
	astrocytosis	J:227618
	decreased body weight	J:227618
	decreased double-positive T cell number	J:227618
	decreased small intestinal villus height	J:227618
	gliosis	J:227618
	microgliosis	J:227618
	neuron degeneration	J:227618
	premature death	J:227618
	small intestinal villus atrophy	J:227618
Ctsdtm1b(EUCOMM)Wtsi/Ctsd+ C57BL/6N-Ctsdtm1b(EUCOMM)Wtsi/Ics	decreased hematocrit	J:211773
	increased circulating aspartate transaminase level	J:211773
Ctsdtm1b(EUCOMM)Wtsi/Ctsdtm1b(EUCOMM)Wtsi C57BL/6N-Ctsdtm1b(EUCOMM)Wtsi/Ics	preweaning lethality, incomplete penetrance	J:211773
Ctsdtm1Cptr/Ctsdtm1Cptr either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd)	abnormal antigen presentation	J:47432
	abnormal crypts of Lieberkuhn morphology	J:28201
	abnormal ileum morphology	J:28201
	abnormal intestinal mucosa morphology	J:28201, J:71688
	abnormal microglial cell morphology	J:71688
	abnormal retina morphology	J:82765
	abnormal spleen B cell follicle morphology	J:28201
	abnormal spleen white pulp morphology	J:28201
	abnormal thrombosis	J:28201
	ataxia	J:28201
	blindness	J:82765
	bradykinesia	J:28201
	normal cellular phenotype	J:28201
	decreased body weight	J:28201, J:71688
	decreased double-positive T cell number	J:28201
	decreased food intake	J:28201
	decreased lymphocyte cell number	J:28201
	increased forebrain apoptosis	J:71688
	lysosomal protein accumulation	J:64892
	premature death	J:28201, J:71688
	retina photoreceptor degeneration	J:82765
	seizures	J:64892, J:71688
	thymus hypoplasia	J:28201
	tonic seizures	J:64892