Cpa3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cpa3
carboxypeptidase A3, mast cell
MGI:88479

13 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cpa3^{tm1.1(KOMP)Vlcg}/Cpa3^{tm1.1(KOMP)Vlcg} C57BL/6N-Cpa3^{tm1.1(KOMP)Vlcg}/Tcp	abnormal kidney morphology	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Cpa3^tm1Hrr/Cpa3^tm1Hrr B6.129P2-Cpa3^tm1Hrr	abnormal response/metabolism to endogenous compounds	J:125964
	increased physiological sensitivity to xenobiotic	J:125964
	increased susceptibility to induced morbidity/mortality	J:125964
	increased susceptibility to xenobiotic induced morbidity/mortality	J:125964
Cpa3^tm1Hrr/Cpa3^tm1Hrr involves: 129P2/OlaHsd * C57BL/6	abnormal mast cell morphology	J:99367
Cpa3^tm2Hrr/Cpa3^tm2Hrr involves: 129P2/OlaHsd	abnormal response/metabolism to endogenous compounds	J:125964
	increased susceptibility to induced morbidity/mortality	J:125964
	increased susceptibility to xenobiotic induced morbidity/mortality	J:125964
Cpa3^tm3(icre)Hrr/Cpa3⁺ B6.129P2-Cpa3^tm3(icre)Hrr	abnormal inflammatory response	J:178942
	absent mast cells	J:178942
	decreased basophil cell number	J:178942
	normal hematopoietic system phenotype	J:178942
	normal immune system phenotype	J:178942
Cpa3^tm3(icre)Hrr/Cpa3⁺ involves: 129P2/OlaHsd * BALB/c * C57BL/6	decreased susceptibility to type I hypersensitivity reaction	J:178942

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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