Comp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Comp
cartilage oligomeric matrix protein
MGI:88469

25 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Comp^tm1Aol/Comp^tm1Aol involves: 129S1/Sv * 129X1/SvJ	abnormal vascular wound healing	J:230573
Comp^tm1Aol/Comp^tm1Aol involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:76781
Comp^tm1Mbri/Comp⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal long bone epiphyseal plate proliferative zone	J:125086
	abnormal pelvic girdle bone morphology	J:125086
	decreased chondrocyte proliferation	J:125086
	increased chondrocyte apoptosis	J:125086
	short tibia	J:125086
Comp^tm1Mbri/Comp^tm1Mbri involves: 129S1/Sv * 129X1/SvJ	abnormal tendon morphology	J:154984
	centrally nucleated skeletal muscle fibers	J:154984
	decreased grip strength	J:154984
	decreased tendon stiffness	J:154984
	increased muscle fatigability	J:154984
	myopathy	J:154984
Comp^tm1Mbri/Comp^tm1Mbri involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal chondrocyte morphology	J:125086
	abnormal hip joint morphology	J:125086
	abnormal ischium morphology	J:125086
	abnormal long bone epiphyseal plate proliferative zone	J:125086
	decreased body weight	J:125086
	decreased chondrocyte proliferation	J:125086
	disproportionate dwarf	J:125086
	increased chondrocyte apoptosis	J:125086
	osteoarthritis	J:125086
	short limbs	J:125086
	short tibia	J:125086
Comp^tm2.1Mbri/Comp⁺ involves: 129S1/Sv * 129X1/SvJ	abnormal long bone epiphyseal plate proliferative zone	J:206511
Comp^tm2.1Mbri/Comp^tm2.1Mbri involves: 129S1/Sv * 129X1/SvJ	abnormal cartilage morphology	J:206511
	abnormal chondrocyte morphology	J:206511
	abnormal chondrocyte physiology	J:206511
	abnormal hip joint morphology	J:206511
	abnormal long bone epiphyseal plate morphology	J:206511
	abnormal long bone epiphyseal plate proliferative zone	J:206511
	abnormal pelvic girdle bone morphology	J:206511
	decreased body weight	J:206511
	disproportionate dwarf	J:206511
	short femur	J:206511
	short tibia	J:206511
	normal skeleton phenotype	J:206511

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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