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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Chrm1
cholinergic receptor, muscarinic 1, CNS
MGI:88396
19 phenotypes from 5 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Chrm1tm1Jwe/Chrm1tm1Jwe
involves: 129S6/SvEvTac * CF-1
abnormal nervous system electrophysiology J:74588
decreased cytotoxic T cell cytolysis J:106393
increased bronchoconstrictive response J:104034
normal nervous system phenotype J:112505
Chrm1tm1Kano/Chrm1tm1Kano
involves: 129X1/SvJ
normal endocrine/exocrine gland phenotype J:105126
Chrm1tm1Kano/Chrm1tm1Kano
involves: 129X1/SvJ * C57BL/6
abnormal inhibitory postsynaptic currents J:98902
Chrm1tm1Kano/Chrm1tm1Kano
involves: 129X1/SvJ * C57BL/6J
normal digestive/alimentary phenotype J:104782
Chrm1tm1Nmn/Chrm1tm1Nmn
B6.129X1-Chrm1tm1Nmn
abnormal auditory cortex morphology J:96239
abnormal auditory cortex tonotopy J:96239
abnormal CNS synapse formation J:96239
normal hearing/vestibular/ear phenotype J:96239
Chrm1tm1Stl/Chrm1+
C57BL/6-Chrm1tm1Stl
hyperactivity J:73448
Chrm1tm1Stl/Chrm1tm1Stl
C57BL/6-Chrm1tm1Stl
hyperactivity J:73448
increased dopamine level J:73448
Chrm1tm1Stl/Chrm1tm1Stl
involves: C57BL/6
abnormal excitatory postsynaptic potential J:112782
decreased paired-pulse facilitation J:112782
reduced long term depression J:112782
Chrm1tm2.1Stl/Chrm1tm2.1Stl
Emx1tm1.1(cre)Ito/0
involves: 129P2/OlaHsd
abnormal excitatory postsynaptic currents J:156540
abnormal long term depression J:156540
abnormal miniature excitatory postsynaptic currents J:156540
decreased paired-pulse facilitation J:156540
Chrm1tm2.1Stl/Chrm1tm2.1Stl
Tg(Grik4-cre)G32-4Stl/0
involves: 129P2/OlaHsd * C57BL/6
abnormal excitatory postsynaptic currents J:156540
abnormal long term depression J:156540
decreased paired-pulse facilitation J:156540

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory