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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cd8b1
CD8 antigen, beta chain 1
MGI:88347
10 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Cd8atm1Asin/Cd8atm1Asin
Cd8b1tm1Litt/Cd8b1tm1Litt
H2-Ab1tm1Gru/H2-Ab1tm1Gru
involves: 129 * FVB/N
decreased CD4-positive, alpha beta T cell number J:126026
increased CD8-positive, alpha-beta T cell number J:126026
Cd8b1tm1Litt/Cd8b1+
Tg(TcraH-Y,TcrbH-Y)71Vbo/0
involves: 129S4/SvJae * C57BL/6J * DBA/2
decreased double-positive T cell number J:112551
Cd8b1tm1Litt/Cd8b1tm1Litt
Tg(TcraH-Y,TcrbH-Y)71Vbo/0
involves: 129S4/SvJae * C57BL/6J * DBA/2
abnormal lymph node cell ratio J:112551
abnormal negative T cell selection J:112551
abnormal positive T cell selection J:112551
decreased CD8-positive, alpha-beta T cell number J:112551
increased CD4-positive, alpha beta T cell number J:112551
Tg(B2M)55Hpl/?
Tg(CD8aCD8b)57Scr/?
Tg(HLA-B)22Hpl/?
involves: C57BL/6 * C57BL/LiA * CBA
abnormal cytotoxic T cell physiology J:127813
Tg(CD8aCD8b)57Scr/?
B6;SJL-Tg(CD8aCD8b)57Scr/J
abnormal cytotoxic T cell physiology J:92994
abnormal effector T cell morphology J:92994

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory