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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Alox5
arachidonate 5-lipoxygenase
MGI:87999
20 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Alox5tm1Bhk/Alox5tm1Bhk
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal inflammatory response J:68714
abnormal neutrophil physiology J:68714
abnormal thromboxane level J:68714
decreased acute inflammation J:68714
decreased leukotriene level J:68714
decreased susceptibility to type I hypersensitivity reaction J:68714
normal hematopoietic system phenotype J:68714
impaired neutrophil chemotaxis J:68714
impaired neutrophil recruitment J:68714
increased prostaglandin level J:68714
Alox5tm1Fun/Alox5tm1Fun
B6.129S2-Alox5tm1Fun
normal immune system phenotype J:89268
Alox5tm1Fun/Alox5tm1Fun
B6.129S2-Alox5tm1Fun/J
decreased susceptibility to experimental autoimmune uveoretinitis J:108446
increased bone mineral density J:104825
increased circulating leptin level J:104825
increased circulating VLDL cholesterol level J:104825
increased total fat pad weight J:104825
Alox5tm1Fun/Alox5tm1Fun
involves: 129S2/SvPas * C57BL/6
abnormal immune system physiology J:21372
normal cardiovascular system phenotype J:21372
decreased inflammatory response J:21372, J:75371
normal hematopoietic system phenotype J:21372
normal immune system phenotype J:21372
small spleen J:21372

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory