Actg1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Actg1
actin, gamma, cytoplasmic 1
MGI:87906

27 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Actg1^{tm1.1(KOMP)Vlcg}/Actg1⁺ C57BL/6N-Actg1^{tm1.1(KOMP)Vlcg}/Ucd	anophthalmia	J:211773
	hemorrhage	J:211773
	microcephaly	J:211773
	microphthalmia	J:211773
	polydactyly	J:211773
	spina bifida	J:211773
	syndactyly	J:211773
Actg1^{tm1.1(KOMP)Vlcg}/Actg1^{tm1.1(KOMP)Vlcg} C57BL/6N-Actg1^{tm1.1(KOMP)Vlcg}/Ucd	anophthalmia	J:211773
	embryonic growth retardation	J:211773
	hemorrhage	J:211773
	microcephaly	J:211773
	microphthalmia	J:211773
	pallor	J:211773
	polydactyly	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	spina bifida	J:211773
	syndactyly	J:211773
Actg1^tm1.1Erv/Actg1^tm1.1Erv B6.129-Actg1^tm1.1Erv	deafness	J:150067
	decreased body weight	J:150067
	decreased outer hair cell stereocilia number	J:150067
	normal digestive/alimentary phenotype	J:150067
	impaired hearing	J:150067
	increased or absent threshold for auditory brainstem response	J:150067
	perinatal lethality, incomplete penetrance	J:150067
	premature death	J:150067
Actg1^tm1.2Erv/Actg1^tm1.2Erv Tg(ACTA1-cre)79Jme/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal skeletal muscle fiber morphology	J:112808
	abnormal Z line morphology	J:112808
	centrally nucleated skeletal muscle fibers	J:112808
	decreased locomotor activity	J:112808
	impaired skeletal muscle contractility	J:112808
	increased variability of skeletal muscle fiber size	J:112808
	limb grasping	J:112808
Actg1^tm1.2Erv/Actg1^tm1.2Erv Tg(Atoh1-cre)1Bfri/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	abnormal cochlear hair cell stereociliary bundle morphology	J:167543
	increased or absent threshold for auditory brainstem response	J:167543
	increased susceptibility to age-related hearing loss	J:167543
Actg1^tm1Erv/Actg1^tm1.1Erv involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cochlear hair cell stereociliary bundle morphology	J:167543
	increased susceptibility to age-related hearing loss	J:167543
Actg1^tm1Erv/Actg1^tm1Erv Tg(ACTA1-cre)79Jme/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal skeletal muscle fiber morphology	J:112808
	abnormal Z line morphology	J:112808
	centrally nucleated skeletal muscle fibers	J:112808
	decreased locomotor activity	J:112808
	impaired skeletal muscle contractility	J:112808
	increased variability of skeletal muscle fiber size	J:112808
	limb grasping	J:112808

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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