Mirc30 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mirc30
microRNA cluster 30, including Mir16-1 through Mir15a
MGI:5315448

12 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd19^tm1(cre)Cgn/Cd19⁺ Mirc30^tm1.1Rdf/Mirc30^tm1.1Rdf involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6	increased B cell derived lymphoma incidence	J:156946
	increased B cell number	J:156946
	increased B-1a cell number	J:156946
	increased leukemia incidence	J:156946
	increased spleen white pulp amount	J:156946
Mirc30^em1Hhzg/Mirc30^em1Hhzg Tg(Vav1-cre)#Cgp/0 involves: 129S4/SvJae * C57BL/6 * C57BL/6NRj	abnormal NK cell morphology	J:320883
	increased B cell number	J:320883
	increased chronic lymphocytic leukemia incidence	J:320883
	increased pre-B cell number	J:320883
	increased pro-B cell number	J:320883
	increased spleen weight	J:320883
Mirc30^tm1.1Mtm/Mirc30^tm1.1Mtm involves: 129P2/OlaHsd * C57BL/6 * FVB	normal mortality/aging	J:181831
Mirc30^tm1.2Rdf/Mirc30^tm1.2Rdf involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6	abnormal B cell proliferation	J:156946
	increased B cell derived lymphoma incidence	J:156946
	increased B cell number	J:156946
	increased B-1a cell number	J:156946
	increased leukemia incidence	J:156946
	increased spleen white pulp amount	J:156946

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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