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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Itgad
integrin, alpha D
MGI:3578624
13 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Itgadtm1.1Zimm/Itgadtm1.1Zimm
involves: 129S6/SvEvTac * C57BL/6
abnormal immune system physiology J:130908
abnormal macrophage physiology J:130908
altered susceptibility to infection J:130908
decreased susceptibility to parasitic infection J:130908
increased circulating interleukin-12 level J:130908
increased spleen weight J:130908
increased susceptibility to bacterial infection J:130908
Itgadtm1Bll/Itgadtm1Bll
B6.129S7-Itgadtm1Bll
abnormal lymphocyte cell number J:90954
abnormal T cell activation J:90954
abnormal T cell subpopulation ratio J:90954
decreased CD4-positive, alpha beta T cell number J:90954
decreased T cell proliferation J:90954
increased CD8-positive, alpha-beta T cell number J:90954

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/08/2020
MGI 6.15
The Jackson Laboratory