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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Card9
caspase recruitment domain family, member 9
MGI:2685628
14 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Card9tm1Jrld/Card9tm1Jrld
involves: 129P2/OlaHsd 		abnormal dendritic cell physiology J:111706
increased susceptibility to fungal infection J:111706
Card9tm1Tks/Card9tm1Tks
B6.129-Card9tm1Tks 		abnormal chemokine secretion J:141143
abnormal cytokine secretion J:122394
abnormal dendritic cell physiology J:122394
abnormal macrophage physiology J:122394, J:141143
decreased interleukin-6 secretion J:160680
decreased interleukin-10 secretion J:160680
decreased interleukin-12b secretion J:160680
decreased interleukin-23 secretion J:160680
decreased tumor necrosis factor secretion J:160680
normal immune system phenotype J:122394
increased susceptibility to bacterial infection J:122394
Card9tm1Xlin/Card9tm1Xlin
involves: 129/Sv * C57BL/6 		abnormal cytokine level J:117799
abnormal innate immunity J:117799
abnormal macrophage physiology J:117799
increased susceptibility to bacterial infection J:117799
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory