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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lexm
lymphocyte expansion molecule
MGI:2681853
12 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
LexmRetro/Lexm+
involves: C57BL/6J
increased CD8-positive, alpha-beta T cell number J:223336
increased cytotoxic T cell cytolysis J:223336
LexmRetro/LexmRetro
involves: C57BL/6J
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:223336
decreased lung tumor incidence J:223336
increased activated T cell number J:223336
increased CD8-positive, alpha-beta T cell number J:223336
increased central memory CD8 positive, alpha-beta T cell number J:223336
increased cytotoxic T cell cytolysis J:223336
increased interferon-gamma secretion J:223336
increased susceptibility to viral infection induced morbidity/mortality J:223336
increased T cell proliferation J:223336
Lexmtm1a(KOMP)Wtsi/Lexm+
involves: C57BL/6
decreased CD8-positive, alpha-beta T cell number J:223336
decreased cytotoxic T cell cytolysis J:223336
Lexmtm1a(KOMP)Wtsi/Lexmtm1a(KOMP)Wtsi
involves: C57BL/6
embryonic lethality J:223336

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/07/2020
MGI 6.14
The Jackson Laboratory