Vsig4 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vsig4
V-set and immunoglobulin domain containing 4
MGI:2679720

27 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Vsig4^{tm1b(EUCOMM)Hmgu}/Y C57BL/6N-Vsig4^{tm1b(EUCOMM)Hmgu}/J	abnormal cholesterol homeostasis	J:211773
	decreased circulating glucose level	J:211773
	decreased locomotor activity	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased total body fat amount	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating potassium level	J:211773
	increased lean body mass	J:211773
	increased urine microalbumin level	J:211773
Vsig4^{tm1b(EUCOMM)Hmgu}/Vsig4^{tm1b(EUCOMM)Hmgu} C57BL/6N-Vsig4^{tm1b(EUCOMM)Hmgu}/J	abnormal sleep behavior	J:211773
	decreased circulating glucose level	J:211773
	decreased total body fat amount	J:211773
	hyperactivity	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating sodium level	J:211773
	increased heart weight	J:211773
	increased lean body mass	J:211773
	increased urine microalbumin level	J:211773
	increased vertical activity	J:211773
Vsig4^tm1Gne/Vsig4^tm1Gne C57BL/6-Vsig4^tm1Gne	abnormal enterocyte proliferation	J:281762
	abnormal macrophage physiology	J:281762
	decreased susceptibility to induced colitis	J:281762
	increased circulating interleukin-1 beta level	J:281762
	increased interleukin-1 beta secretion	J:281762
	increased susceptibility to experimental autoimmune encephalomyelitis	J:281762
	increased T-helper 1 cell number	J:281762
	increased T-helper 17 cell number	J:281762
Vsig4^tm1Gne/Vsig4^tm1Gne involves: C57BL/6N	increased susceptibility to bacterial infection	J:138691
Vsig4^tm1Gne/Vsig4^tm1Gne involves: C57BL/6N	increased susceptibility to induced morbidity/mortality	J:138691

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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