Thoc6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Thoc6
THO complex 6
MGI:2677480

18 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Thoc6^em1Schaf/Thoc6⁺ C57BL/6JN-Thoc6^em1Schaf	no abnormal phenotype detected	J:345604
Thoc6^em1Schaf/Thoc6^em1Schaf C57BL/6JN-Thoc6^em1Schaf	abnormal telencephalon development	J:345604
	decreased embryo size	J:345604
	embryonic growth retardation	J:345604
	embryonic lethality during organogenesis, complete penetrance	J:345604
	increased embryonic neuroepithelial cell proliferation	J:345604
	increased embryonic tissue cell apoptosis	J:345604
Thoc6^em5(IMPC)Tcp/Thoc6⁺ C57BL/6NCrl-Thoc6^em5(IMPC)Tcp/Tcp	abnormal lung morphology	J:211773
	decreased exploration in new environment	J:211773
	decreased locomotor activity	J:211773
	decreased vertical activity	J:211773
	enlarged lymph nodes	J:211773
	enlarged ovary	J:211773
	increased anxiety-related response	J:211773
	shortened QRS complex duration	J:211773
Thoc6^em5(IMPC)Tcp/Thoc6^em5(IMPC)Tcp C57BL/6NCrl-Thoc6^em5(IMPC)Tcp/Tcp	abnormal embryo size	J:211773
	embryonic growth retardation	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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