Btla Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Btla
B and T lymphocyte associated
MGI:2658978

13 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Btla^tm1Dgra/Btla^tm1Dgra involves: C57BL/6	abnormal peripheral T cell anergy	J:147751
Btla^tm1Dgra/Btla^tm1Dgra involves: C57BL/6	abnormal T cell activation	J:147751
Btla^tm1Kay/Btla^tm1Kay involves: 129S6/SvEvTac * C57BL/6J	abnormal T cell activation	J:89864
Btla^tm1Kmm/Btla^tm1Kmm B6.129S-Btla^tm1Kmm	abnormal T cell activation	J:119356
	decreased interferon-gamma secretion	J:119356
	decreased interleukin-2 secretion	J:119356
	decreased T cell proliferation	J:119356
	increased length of allograft survival	J:119356
	increased T cell proliferation	J:119356
Btla^tm1Kmm/Btla^tm1Kmm involves: 129S/SvEv	abnormal humoral immune response	J:84084
	increased B cell proliferation	J:84084
	increased IgG1 level	J:84084
	increased IgG2a level	J:84084
	increased IgG2b level	J:84084
	increased susceptibility to experimental autoimmune encephalomyelitis	J:84084
	increased T cell proliferation	J:84084

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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