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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Fancd2
Fanconi anemia, complementation group D2
MGI:2448480
45 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Aldh2tm1a(EUCOMM)Wtsi/Aldh2+
Fancd2tm1Hou/Fancd2tm1Hou
involves: 129S4/SvJae * C57BL/6J * C57BL/6N
abnormal eye morphology J:193232
exencephaly J:193232
Aldh2tm1a(EUCOMM)Wtsi/Aldh2tm1a(EUCOMM)Wtsi
Fancd2tm1Hou/Fancd2+
involves: 129S4/SvJae * C57BL/6J * C57BL/6N
maternal effect J:193232
Aldh2tm1a(EUCOMM)Wtsi/Aldh2tm1a(EUCOMM)Wtsi
Fancd2tm1Hou/Fancd2tm1Hou
involves: 129S4/SvJae * C57BL/6J * C57BL/6N
abnormal bone marrow cell morphology/development J:193232
abnormal chest morphology J:193232
abnormal eye morphology J:193232
abnormal hematopoietic stem cell physiology J:188123
abnormal lymphopoiesis J:193232
abnormal spleen morphology J:188123
abnormal thymus morphology J:188123
anemia J:188123, J:193232
anophthalmia J:193232
decreased body weight J:193232
decreased bone marrow cell number J:188123, J:193232
decreased erythrocyte cell number J:188123, J:193232
decreased hematocrit J:188123
decreased hematopoietic stem cell number J:188123
decreased hemoglobin content J:188123, J:193232
decreased leukocyte cell number J:188123
embryonic lethality during organogenesis J:193232
enlarged spleen J:193232
exencephaly J:193232
extramedullary hematopoiesis J:188123
impaired hematopoiesis J:193232
increased acute lymphoblastic leukemia incidence J:193232
increased CD8-positive, alpha-beta T cell number J:193232
increased double-positive T cell number J:193232
increased lymphoma incidence J:193232
increased mean corpuscular volume J:188123
increased physiological sensitivity to xenobiotic J:188123
increased sensitivity to induced cell death J:188123
increased sensitivity to xenobiotic induced morbidity/mortality J:193232
increased T cell derived lymphoma incidence J:193232
kinked tail J:193232
lethargy J:193232
pancytopenia J:188123
premature death J:193232
thrombocytopenia J:188123
weight loss J:193232
Brip1Gt(RRI409)Byg/Brip1Gt(RRI409)Byg
Fancd2tm1Hou/Fancd2tm1Hou
involves: 129P2/OlaHsd * 129S4/SvJae
abnormal seminiferous tubule morphology J:227115
increased cellular sensitivity to DNA damaging agents J:227115
small testis J:227115
Dclre1atm1Remo/Dclre1atm1Remo
Fancd2tm1Hou/Fancd2tm1Hou
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6J
perinatal lethality, incomplete penetrance J:134461
Fan1tm1.1Jrou/Fan1tm1.1Jrou
Fancd2Gt(OST57859)Lex/Fancd2Gt(OST57859)Lex
involves: 129P2/OlaHsd * 129S5/SvEvBrd
increased physiological sensitivity to xenobiotic J:232403
Fan1tm1d(KOMP)Wtsi/Fan1tm1d(KOMP)Wtsi
Fancd2tm1Hou/Fancd2tm1Hou
involves: 129S4/SvJae * C57BL/6N * FVB/N
abnormal hematopoietic stem cell morphology J:232402
increased physiological sensitivity to xenobiotic J:232402
Fancd2Gt(OST57859)Lex/Fancd2Gt(OST57859)Lex
Usp1tm1.1Ada/Usp1tm1.1Ada
involves: 129S5/SvEvBrd * C57BL/6
increased cellular sensitivity to ionizing radiation J:146616
induced chromosome breakage J:146616
ovary atrophy J:146616

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory