46 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Aldh2tm1a(EUCOMM)Wtsi/Aldh2+ Fancd2tm1Hou/Fancd2tm1Hou involves: 129S4/SvJae * C57BL/6J * C57BL/6N	abnormal eye morphology	J:193232
	exencephaly	J:193232
Aldh2tm1a(EUCOMM)Wtsi/Aldh2tm1a(EUCOMM)Wtsi Fancd2tm1Hou/Fancd2+ involves: 129S4/SvJae * C57BL/6J * C57BL/6N	maternal effect	J:193232
Aldh2tm1a(EUCOMM)Wtsi/Aldh2tm1a(EUCOMM)Wtsi Fancd2tm1Hou/Fancd2tm1Hou involves: 129S4/SvJae * C57BL/6J * C57BL/6N	abnormal bone marrow cell morphology/development	J:193232
	abnormal chest morphology	J:193232
	abnormal eye morphology	J:193232
	abnormal hematopoietic stem cell physiology	J:188123
	abnormal lymphopoiesis	J:193232
	abnormal spleen morphology	J:188123
	abnormal thymus morphology	J:188123
	anemia	J:188123, J:193232
	anophthalmia	J:193232
	decreased body weight	J:193232
	decreased bone marrow cell number	J:188123, J:193232
	decreased erythrocyte cell number	J:188123, J:193232
	decreased hematocrit	J:188123
	decreased hematopoietic stem cell number	J:188123
	decreased hemoglobin content	J:188123, J:193232
	decreased leukocyte cell number	J:188123
	embryonic lethality during organogenesis	J:193232
	enlarged spleen	J:193232
	exencephaly	J:193232
	extramedullary hematopoiesis	J:188123
	impaired hematopoiesis	J:193232
	increased acute lymphoblastic leukemia incidence	J:193232
	increased CD8-positive, alpha-beta T cell number	J:193232
	increased double-positive T cell number	J:193232
	increased lymphoma incidence	J:193232
	increased mean corpuscular volume	J:188123
	increased physiological sensitivity to xenobiotic	J:188123
	increased sensitivity to induced cell death	J:188123
	increased susceptibility to xenobiotic induced morbidity/mortality	J:193232
	increased T cell derived lymphoma incidence	J:193232
	kinked tail	J:193232
	lethargy	J:193232
	pancytopenia	J:188123
	premature death	J:193232
	thrombocytopenia	J:188123
	weight loss	J:193232
Brip1Gt(RRI409)Byg/Brip1Gt(RRI409)Byg Fancd2tm1Hou/Fancd2tm1Hou involves: 129P2/OlaHsd * 129S4/SvJae	abnormal seminiferous tubule morphology	J:227115
	increased cellular sensitivity to DNA damaging agents	J:227115
	small testis	J:227115
Dclre1atm1Remo/Dclre1atm1Remo Fancd2tm1Hou/Fancd2tm1Hou involves: 129S4/SvJae * 129X1/SvJ * C57BL/6J	perinatal lethality, incomplete penetrance	J:134461
Fan1tm1.1Jrou/Fan1tm1.1Jrou Fancd2Gt(OST57859)Lex/Fancd2Gt(OST57859)Lex involves: 129P2/OlaHsd * 129S5/SvEvBrd	increased physiological sensitivity to xenobiotic	J:232403
Fan1tm1d(KOMP)Wtsi/Fan1tm1d(KOMP)Wtsi Fancd2tm1Hou/Fancd2tm1Hou involves: 129S4/SvJae * C57BL/6N * FVB/N	abnormal hematopoietic stem cell morphology	J:232402
	increased physiological sensitivity to xenobiotic	J:232402
Fancd2Gt(OST57859)Lex/Fancd2Gt(OST57859)Lex Fancitm1.1Itl/Fancitm1.1Itl involves: 129S5/SvEvBrd * C57BL/6J * CBA	abnormal bone marrow cell morphology/development	J:285384
	decreased hematopoietic stem cell number	J:285384
	prenatal lethality, incomplete penetrance	J:285384
	thrombocytopenia	J:285384
Fancd2Gt(OST57859)Lex/Fancd2Gt(OST57859)Lex Usp1tm1.1Ada/Usp1tm1.1Ada involves: 129S5/SvEvBrd * C57BL/6	increased cellular sensitivity to ionizing radiation	J:146616
	induced chromosome breakage	J:146616
	ovary atrophy	J:146616