Vps33b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vps33b
vacuolar protein sorting 33B
MGI:2446237

26 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Vps33b^tm1.1Arte/Vps33b^tm1.1Arte Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor⁺ involves: C57BL/6 * C57BL/6J	abnormal megakaryocyte morphology	J:222766
	abnormal tendon collagen fibril morphology	J:236095
	alopecia	J:236095
	decreased dendritic cell number	J:222766
	decreased lymphocyte cell number	J:222766
	decreased mean platelet volume	J:222766
	decreased platelet aggregation	J:222766
	decreased platelet alpha-granule number	J:222766
	dry skin	J:222766, J:236095
	enlarged spleen	J:222766
	extramedullary hematopoiesis	J:222766
	normal growth/size/body region phenotype	J:236095
	increased bleeding time	J:222766
	increased macrophage cell number	J:222766
	increased megakaryocyte cell number	J:222766
	increased monocyte cell number	J:222766
	increased neutrophil cell number	J:222766
	scaly skin	J:222766, J:236095
	skin lesions	J:222766
	thrombocytosis	J:222766
Vps33b^{tm1a(EUCOMM)Wtsi}/Vps33b⁺ C57BL/6N-Vps33b^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal thoracic cage shape	J:211773
	increased circulating HDL cholesterol level	J:211773
Vps33b^{tm1a(EUCOMM)Wtsi}/Vps33b^{tm1a(EUCOMM)Wtsi} C57BL/6N-Vps33b^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal placenta morphology	J:261316
	abnormal trophoblast layer morphology	J:261316
	embryonic lethality during organogenesis, complete penetrance	J:261316
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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